Cardinals vs 49ers MNF Spread Odds and Prediction

The Arizona Cardinals and the San Francisco 49ers will square off in a NFC West divisional battle tonight for the December 14th Monday Night Football game.  The Arizona Cardinals (8-4) sit a top the AFC West division, while the San Francisco 49ers (5-7) in second are looking to make a late season push for the post season.  These two teams met in their season opener game, where the 49ers came out on top 20-16.  The Cardinals are coming off an impressive 30-17 win over the Minnesota Vikings last Sunday night, after a three point loss to Tennessee in the prior week.  The 49ers are struggling after a good start to the season, losing six of their last eight games.  Last week they were beat in Seattle 20-17 with a last minute field goal from the Seahawks.  This primetime game promises to be exciting, as the 49ers will be playing as if it is a do or die game to keep their playoff hopes alive.  Get your Cardinals vs 49ers betting spread, odds, trends and our prediction on the game below.

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Cardinals vs 49ers Betting Spread and Odds:


Arizona Cardinals -3.5 (-110)
vs San Francisco 49ers +3.5 (-110)

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Over Under:

Over 45 points (-110)
Under 45 points (-110)

Cardinals vs 49ers Betting Trends:

Cardinals are 6-1 ATS in their last 7 road games
49ers are 6-2-1 ATS in their last 9 home games
Cardinals are 4-0 ATS in their last 4 meetings in San Fran
Road team is 8-0 ATS in their last 8 meetings

Cardinals vs 49ers Predictions:

Final Score Prediction – Cardinals 24 @ 49ers 17

Spread Prediction – I like the CARDINALS to cover the 3.5 point spread in tonight’s MNF game.  Kurt Warner is playing too good right now – in his last four starts he has put up a 120+ QB rating in each game.  The 49ers have the 27th ranked pass defense in the NFL, which should get picked apart by Warner.  The 49ers have played tough at home this season, but I don’t think they will have enough to stop this Cardinals team who is content on heading to the postseason hot.  Bet the CARDINALS on the spread.

A $20 bet on either team on the spread would pay out $38 at

Over Under Prediction – I like the UNDER 45 total points (-110) in this Cardinals vs 49ers game.  The under has gone 4-0 in the Cardinals last 4 games as a road favorite, and 5-0 in 49ers last 5 against division opponents.  The 49ers have been good defensively at home, allowing 10 points or less in four of their six home games.  The Cardinals offense has been kept under 25 points in three of their last four road games.  Bet the UNDER in tonight’s Monday Night Cardinals/49ers match up.

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