Baltimore Orioles vs. New York Yankees Pick – MLB April 7, 2021

The Baltimore Orioles and New York Yankees will meet for the third and final time of this three-game series on Wednesday evening. The Yankees have made it look easy over the first two games against the Orioles. They throttled the O’s by a score of 7-0 and 7-2 last night. The Yankees were on track to make it another 7-0 win before the Orioles added a couple of garbage time runs to finally get on the board against the Yankees.

The first of two wins was Giancarlo Stanton’s night, as he quieted the home crowd with a grand slam. Yes, quieted the home crowd. Stanton has heard the boo birds already this season. Struggling against the Toronto Blue Jays in the season opening series, the Yankees’ fans were letting Stanton have it. The Blue Jays won that series with two wins in three games, people in the Bronx were not happy at Yankee Stadium.

The Yankees have responded in fine form, though, as they’ve belted the Orioles in two straight games. Last night it was Aaron Judge’s turn, as he went 3-for-5 with 4 RBI. Stanton added another RBI to tack on one more for 5 on the season. After going RBI-less against the Blue Jays, Stanton has recorded 5 in two games to silence his critics at Yankee Stadium. Gerrit Cole was fantastic for the Yanks on Tuesday night. Cole pitched 7 innings with 4 hits and no runs allowed. He also struck out 13 hitters for a big night at the office.

Dean Kremer lasted 3 innings with 5 hits, 4 walks, and 3 earned runs allowed. Tough assignment for Kremer at Yankee Stadium, but he did enough to prevent the game from completely getting out of hand early. The offense was doing nothing anyway, so it doesn’t matter what Kremer was doing on the hill. The Orioles will turn to John Means to get a positive response on Wednesday evening at Yankee Stadium. He is coming off a big performance against the Boston Red Sox on April 2.

The Yankees will be expected to counter with former Pittsburgh Pirate, Jameson Taillon. Taillon hasn’t pitched since 2019 in a regular season game. He spent last year rehabbing from Tommy John surgery and will finally make his return to the bump with the Yankees on Wednesday night. The 29-year-old has shown promise at times in his career, but the injury really derailed things. He gets a fresh start with the Yankees. Head below for our free Orioles vs. Yankees pick on April 7, 2021.

Baltimore Orioles vs. New York Yankees MLB Betting Odds:


  • Orioles +1.5 (-110)
  • Yankees -1.5 (-110)

  • Orioles +167
  • Yankees -182

  • Over 9.5 (+105)
  • Under 9.5 (-125)


Orioles vs. Yankees Prediction:

John Means has been a pitcher tough to put a finger on. He was expected to be a major contributor for the Orioles growing up in the organization since 2014. However, Means has only participated in one full season in the major leagues. He was solid through 31 appearances in 2019, posting an ERA of 3.60 and 1.14 WHIP through 155 innings. It was a promising season after Means was creamed in a brief appearance in 2018 with a 13.50 ERA and 1.80 WHIP conceded in 3.1 innings.

Means made ten starts last year and was serviceable. I don’t think it was what the Orioles were looking for, but Means was adequate with a 4.53 ERA through 43.2 innings. He had trouble keeping the ball in the park, as he was smacked for 12 home runs and 22 earned runs. Games where Means was pitching well turned to losses in a hurry because of his inability to keep the ball down.

The Yankees have hit 4 home runs against Means in 60 at-bats to go with a .243 batting average and .358 OBP. They’ve recorded 12 RBI against Means during that time. The Yankees’ bats are hot right now, and I can see them giving Means a rough time. Having said that, Means looked great in his season opener, allowing just 1 hit and no runs through 7 innings on the hill. He has some momentum, but can see some regression for him.

Means struggled in spring training, as he finished with a 7.11 ERA and 1.42 WHIP across 19 innings of work. The Yankees likely don’t blow him up tonight, though don’t expect Means to do what he did against the Red Sox. His counterpart, James Taillon, has been waiting a long time to get back on the bump. Taillon posted an ERA of 3.20 and 1.18 WHIP when he was in peak form in 2018 with the Pirates.

He followed up with a 4.10 ERA and 1.13 WHIP the following season before a shoulder injury sent him to the operating table after seven starts. Taillon has been strong in spring training. He posted an ERA of 1.08 ERA through 8.1 innings. In his limited experience against the O’s, he’s done well to hold them to a 0.83 average and .135 OBP in 15 at-bats. At an affordable price, the Yankees on the runline is a good option Wednesday.


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Kyle E / Author

Kyle is a veteran of TheSportsGeek and has spent nearly a decade providing accurate sports picks and writeups here. He has been a sports handicapper for 10+ years and started sharing his picks and thoughts in 2011 at TheSportsGeek. His expertise spans across multiple sports, including the NFL, NCAAF, MLB, NHL, and horse racing. Prior to writing for TheSportsGeek, Kyle was a fantasy football expert, who ultimately parlayed it into a successful sports betting career. You can find his picks daily only at TheSportsGeek.