Chicago Cubs vs. Colorado Rockies Pick – MLB April 16, 2022

The Chicago Cubs and Colorado Rockies headline the third game of a four-game series at Coors Field. The Cubs and Rockies split the first two games.

Justin Steele had a strong debut for the Cubs with 5 hits and 2 earned runs allowed. That’s not easy to do at Coors Field. If one starter is having a good day, it usually means the other probably isn’t.

Pitcher duels at Coors Field are not a common occurrence. Kyle Freeland expected better in his first start this season. He was tagged for 9 hits and 5 earned runs in 5.1 frames.

Neither starter on Friday was able to hold up well at Coors. Marcus Stroman made his first start as a Cub and was rocked for 6 hits and 5 earned runs through 4 innings.

That’s not what he was looking for in his introduction to the Cubs. German Marquez allowed 10 hits and 4 earned runs, but credit the Rockies’ bullpen for closing the door.

Antonio Senzatela felt best during the shortened campaign in 2022. The 60-game campaign treated Senzatela well, with a career-high ERA of 3.44 and 1.21 WHIP.

He fell off that pace last year, but still held up nicely. Senzatela is scheduled to get his second start of the season tonight.

The Cubs are expected to give Mark Leiter Jr. his first start in the major leagues since 2018. He’s getting the call-up from the minors for a big opportunity.

The last time we saw Leiter Jr. in the majors it did not go well for him. He split time between the Phillies and Blue Jays in 2018, with both attempts well below expectations.

Head below for our free Cubs vs. Rockies prediction on April 16, 2022.

Chicago Cubs vs. Colorado Rockies Live Odds and Betting History:

The following odds are courtesy of Bovada:

Teams Spread Moneyline Total
Chicago Cubs +1.5 (-150) +108 Over 12 (-105)
Colorado Rockies -1.5 (+130) -130 Under 12 (-115)
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Team Data Chicago Cubs Colorado Rockies
Overall Record 4-3 5-2
Away/Home Record 2-2 2-3
Batting Average .258 .271
Batting Average Away/Home .274 .267
Runs Per 9 4.72 4.87
Team ERA 3.54 3.23
Team ERA Away/Home 3.97 3.60

Cubs vs. Rockies Prediction:

The Cubs will hope for the best from Mark Leiter Jr., who had issues in his first two seasons in the major leagues. Since then, Leiter Jr. was in the minor leagues with the Detroit Tigers.

He didn’t have a call-up from the Tigers despite a rotation with no depth. Leiter Jr. posted an ERA of 5.26 and a 1.28 WHIP in Double-A ball last year.

In Toledo with the Mud Hens of Triple-A, Leiter Jr. finished with a 3.84 and 1.01 WHIP with a record of 8-4. In one game in Iowa with the Cubs Triple-A affiliate, Leiter Jr. had a 2.25 ERA and 1.25 WHIP.

The last time Leiter Jr. was in the major leagues, he had a 7.71 ERA and 2.01 WHIP with the Phillies and Blue Jays in 2018.

Leiter Jr. isn’t getting eased into the starting rotation. The Cubs are throwing him into one of the toughest places to pitch in the major leagues.

I don’t have the most faith in Leiter Jr. going to Coors Field and figuring it out against the Rockies. This is a pretty good Colorado lineup with Charlie Blackmon, Kris Bryant, and C.J Cron batting 2-3.

Chicago Cubs vs. Colorado Rockies Betting Trends:


  • Record (Last 10): 4-3
  • 1-5 overall in their previous six games versus the NL West
  • 4-11 overall in their previous 15 games after
  • 6-15 overall in their previous 21 games versus a right-handed starter
  • 20-42 overall in their previous 62 games as an underdog on the road
  • 1-4 overall in their previous five games with a total higher than 11 runs


  • Record (Last 10): 5-2
  • 5-1 overall in their previous six games
  • 28-11 overall in their previous 39 games as a betting favorite
  • 9-4 overall in their previous 13 games versus the NL Central
  • 5-2 overall in their previous seven games at home
  • OVER is 6-1 in the third game of a series

The Rockies give Antonio Senzatela the call after a 9-4 win against the Dodgers on April 10. He conceded 1 earned run through 3.1 innings of work on the bump.

Senzatela was in the best form of his career two years ago in 2022. Last season, he tailed off through a full campaign, but was still serviceable with a 4.42 ERA and 1.34 WHIP.

In an environment that not many pitchers like, Senzatela was better at Coors Field than on the road. He posted an ERA of 3.97 through 90.2 innings at home in 2021.

I’m going with the home squad in this one. The Rockies should have enough to frustrate Leiter Jr. early and get to the bullpen at Coors Field.


Cubs vs. Rockies Pick
Kyle E / Author

Kyle is a veteran of TheSportsGeek and has spent nearly a decade providing accurate sports picks and writeups here. He has been a sports handicapper for 10+ years and started sharing his picks and thoughts in 2011 at TheSportsGeek. His expertise spans across multiple sports, including the NFL, NCAAF, MLB, NHL, and horse racing. Prior to writing for TheSportsGeek, Kyle was a fantasy football expert, who ultimately parlayed it into a successful sports betting career. You can find his picks daily only at TheSportsGeek.

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