Chicago White Sox vs. Kansas City Royals Pick – MLB May 18, 2022

The Chicago White Sox and Kansas City Royals have two more games in a lengthy five-game series. They played a doubleheader at Kauffman Stadium yesterday to make up for a previous postponement.

The White Sox won the first game, 3-0, to win the first two games of the series. Dylan Cease made it through 5.2 innings, as he didn’t give up a run in the shutout for the White Sox. The Royals threatened him with 7 hits, but Cease held well.

The Royals came back in the nightcap with a 2-1 win behind Brady Singer. The Gator is quickly turning into the ace of the club.

It’s been a mighty slow start in the AL Central this season. The White Sox are expected to play better baseball than they’ve shown so far. There is only one team in the division with a record better than .500.

The White Sox are currently 2.5 games behind the Minnesota Twins in the AL Central. The Twins are the lone team above .500 going into this one.

The White Sox are a .500 club at 18-18 after the split in the doubleheader on Wednesday.

The Royals are 13-22, but they weren’t expected to be a hugely competitive team. This is on par for the Royals, but the White Sox aren’t living up to pre-season projects, at least so far.

Lucas Giolito is getting the call on the bump for the White Sox tonight. He’s back after having a start pushed back because of going on the Covid-19 list.

This is a pretty good pitching matchup on paper at Kauffman Stadium, with the Royals countering Giolito with veteran Zack Greinke. The Royals is the right place for Greinke to finish his career.

Head below for our free White Sox vs. Royals pick on May 18, 2022.

Chicago White Sox vs. Kansas City Royals Live Betting Odds:

The following odds are courtesy of Bovada:
Teams Spread Moneyline Total
Chicago White Sox -1.5 (+105) -150 Over 8 (-120)
KC Royals +1.5 (-125) +126 Under 8 (+100)
Betting Site
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3 BetUS

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4 Everygame

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5 MyBookie

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Team Data Chicago White Sox KC Royals
Overall Record 18-18 13-22
Away/Home Record 9-8 7-11
Batting Average .227 .224
Batting Average Away/Home .229 .225
Runs Per 9 3.53 3.54
Team ERA 3.71 4.49
Team ERA Away/Home 3.14 4.03

White Sox vs. Royals Prediction:

Lucas Giolito will have to shake off the Covid-19 rust and pitch at Kauffman Stadium tonight. He’s been in decent form when active, as Giolito enters Kansas City with an ERA of 2.70 and a 1.12 WHIP.

Giolito is going into Kauffman with a 3.38 ERA and 1.07 WHIP in his last three tilts. He allowed 3 earned runs against the Angels and Cubs, but bounced back with 1 earned run versus Cleveland eight days ago.

The bullpen could pitch better for the White Sox this season. The White Sox have a bullpen ERA of 4.06 and a 1.35 WHIP. They aren’t that much better than the Royals, with a 4.16 ERA and 1.38 WHIP.

The White Sox bats have been the most disappointing aspect of this season.

They’re hitting .227 with 3.51 runs per 9 innings in 26th. On the road this season, the White Sox have scored just 3.29 runs per 9 innings. Their lineup has to be better than this at the plate.

Zack Greinke has contained this White Sox roster in his career. The White Sox are hitting .203 with a .242 versus Greinke in 109 at-bats.

Chicago White Sox vs. KC Royals Betting Trends:

White Sox

  • Record (Last 10): 5-5
  • 8-2 overall in their previous ten games as a betting favorite
  • 5-1 overall in their previous six games as a betting favorite on the road
  • 2-7 overall in their previous nine games in the fourth game of a series
  • 4-9 overall in their previous 13 games versus the NL Central
  • UNDER is 4-0 in their previous four games


  • Record (Last 10): 4-6
  • 6-12 overall in their previous 18 games
  • 3-6 overall in their previous nine games on a Wednesday
  • 7-19 overall in their previous 26 games as an underdog
  • UNDER is 9-1 in their previous ten games versus the White Sox at home
  • UNDER is 4-1 in their previous five games versus the American League

  • Greinke has looked comfortable back where it all started in his career at Kauffman Stadium. Greinke is entering this matchup with an ERA of 2.25 and a 1.19 WHIP in 16 innings at home.

    Overall, Greinke has posted a respectable ERA of 3.52 and a 1.17 WHIP in 39 innings of work.

    Greinke is coming off his worst performance this season after allowing 8 hits and 5 earned runs through 4.2 innings. This was at Coors Field against the Colorado Rockies, the toughest park to pitch in baseball.

    Look for Greinke to bounce back with a strong performance at Kauffman Stadium. The White Sox are playing well below expectations at the plate this season.

    I’m not that excited about laying -150 on the White Sox on the road tonight. They have been overpriced often this season, and I’m not running to the window to fade Greinke at home.

    For a better bet at a better price, I’d look at the Royals runline to cover 1.5 runs. This is likely another close one with the game decided by a run.


    White Sox vs. Royals Pick
    KC ROYALS +1.5
Kyle E / Author

Kyle is a veteran of TheSportsGeek and has spent nearly a decade providing accurate sports picks and writeups here. He has been a sports handicapper for 10+ years and started sharing his picks and thoughts in 2011 at TheSportsGeek. His expertise spans across multiple sports, including the NFL, NCAAF, MLB, NHL, and horse racing. Prior to writing for TheSportsGeek, Kyle was a fantasy football expert, who ultimately parlayed it into a successful sports betting career. You can find his picks daily only at TheSportsGeek.

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