Chicago White Sox vs. Los Angeles Angels Pick – MLB April 2, 2021

The Chicago White Sox and Los Angeles Angels will meet for the second game of a four-game series in Anaheim on Friday night. It was a tight one at Angel Stadium on Opening Day. The White Sox jumped out to an early lead in the 2nd inning by a run, and then added a couple of runs in the 5th frame to take a 3-1 lead. Up by a run in the bottom of the 8th, the Angels sparked by Albert Pujols, scored 2 to take a 4-3 lead. Rasiel Iglesias went 1-2-3 to close out the White Sox for a nice opener for the Angels.

The most important thing to take from Opening Day is to not get too invested emotionally in what happened. This is a very long marathon of 162 games. Don’t overreact to good teams that maybe didn’t win, and bad teams that came up with a nice win. A lot changes over the course of a season. If you blink, you’ll miss what is going on in the majors.

And when it comes to your own betting, don’t get too down if you opened with a bad day. Baseball is the ultimate grind when it comes to sports betting. You are going to have ups and downs throughout a season that extends all the way to the end of October. For the White Sox, I hope they weren’t reading what the media was saying about them too much in the offseason.

If they buy into the hype too much, that’s when getting complacent and too comfortable happens. There is always one or two teams, in every sport, that receives a lot of pre-season hype and things don’t pan out right. Maybe the White Sox are going to be that team in 2021. If they do get off to a slow start, I wouldn’t jump to any conclusions just yet, though. It’s a long season.

Lucas Giolito was sharp early for the White Sox. He was rolling and it didn’t look like the Angels were going to hit him. The Angels got to Giolito for 2 earned runs, while Dylan Bundy pitched 6 strong innings with 6 hits and 3 earned runs allowed. Former Houston Astro, Dallas Keuchel, who made his debut with the White Sox last season, will get his first nod of 2021 tonight. It’s lefty against lefty, with Andrew Heaney countering for the Angels. Head below for our free White Sox vs. Angels pick on April 2, 2021.

Chicago White Sox vs. Los Angeles Angels MLB Betting Odds:


  • White Sox +1.5 ( -198)
  • Angels -1.5 (+173)

  • White Sox +105
  • Angels -115

  • Over 8.5 (-116)
  • Under 8.5 (-104)


White Sox vs. Angels Prediction:

Dallas Keuchel was phenomenal for the White Sox through a short sample of games in the shortened season. He registered a career-high ERA of 1.99 and 1.09 WHIP through 11 starts and 63.1 innings. It’s hard to compare this to a full season, but last season was a great response for Keuchel after posting a 3.74 and 3.75 ERA in his final two years in Houston. Keuchel regressed from a 2.90 ERA in 2017, but looked to be in 2017 form in Chicago with the White Sox. Keuchel has been lights out against the Angels in his career.

This Angels roster is hitting .158 with a .238 OBP against Keuchel in 149 at-bats. Don’t give Pujols anything juicy to hit, and Keuchel should be fine. Pujols has swatted 3 home runs against Keuchel in 39 at-bats. Mike Trout and Pujols are responsible for all of the long balls against Keuchel, with Trout connecting for 2 home runs. In any case, Keuchel has done a great job at keeping runners off the bases against the Angels. Conversely, Andrew Heaney hasn’t been in the same shape against this White Sox team.

The White Sox are hitting .280 with a .328 OBP versus Heaney through 36 at-bats. Jose Abreu has accounted for 2 home runs and 4 RBI against Heaney. The Angels’ rotation has long struggled with consistency. They are hoping that Heaney can have a breakout season in 2021. Heaney has posted an ERA above the 4.00 in five straight years. After yielding a 3.49 ERA as a sophomore in 2015, Heaney has been unable to match that form. After posting a 4.15 ERA in 2018, Heaney notched an ERA of 4.91 and 4.46 the last two years.

In his final four games of the regular season in 2020, he allowed at least 3 earned runs in every start. Heaney did not have a fun spring training this season. He was well out of form with a 7.41 ERA and 1.65 WHIP through 17 innings. Heaney conceded 19 hits and 4 home runs during spring training. That isn’t always the best barometer for future success in the regular season, but I’m certainly not running to the window to pay -115 on Heaney. I would rather take my chances on getting Keuchel at +105. The White Sox look like a good value play.


Our Bet
Kyle E / Author

Kyle is a veteran of TheSportsGeek and has spent nearly a decade providing accurate sports picks and writeups here. He has been a sports handicapper for 10+ years and started sharing his picks and thoughts in 2011 at TheSportsGeek. His expertise spans across multiple sports, including the NFL, NCAAF, MLB, NHL, and horse racing. Prior to writing for TheSportsGeek, Kyle was a fantasy football expert, who ultimately parlayed it into a successful sports betting career. You can find his picks daily only at TheSportsGeek.