Cleveland Indians vs. Cincinnati Reds Pick – MLB April 16, 2021

The Cleveland Indians and Cincinnati Reds are expected to get a three-game interleague series underway at the Great American Ball Park on Friday night in Cincinnati. A day after allowing Carlos Rodon to no-hit them, the Indians bounced back against the White Sox on Thursday with a 4-2 win. Aaron Civale spun a solid game for the Tribe, as he allowed 1 earned run across 6 innings of work.

The Indians took a split in that series in Chicago, which they will certainly be content with on the road against a quality White Sox squad. They were blown out, 8-0, with no hits against Rodon, but it was otherwise a competitive series for the Indians at Guaranteed Rate Field. The Indians will stay on the road for an in-state battle against the Reds.

Cleveland is currently second in the AL Central with a record of 7-5. They are a half game behind the Kansas City Royals, who have gotten off to a nice 7-4 start. People have been sleeping on the Royals since they fell off after winning the World Series, but there is enough talent on their team to likely make them a dark horse to win the division.

Having said that, this is a wide open division, and the White Sox, despite a 6-7 opening stretch, are likely the team to beat. It’s too early to write off a White Sox team that has only played 13 games. The AL Central is going to be there for the taking for any team, including the Indians who might be able to squeak in. The Indians might have lost Francisco Lindor, but their pitching staff is still going to continue to be tough to hit.

The Reds are coming off back-to-back losses against the San Francisco Giants, 7-6 and 3-0. Those are two very different ways to lose a game. In the first outing, the Reds came up short by a run in a high-scoring affair. Luis Castillo was rocked for 7 hits and 4 earned runs through 5 innings.

Without Castillo pitching well this season, the Reds are going to be a doomed operation. They need Castillo throwing flame throwing darts for success and a chance at the division. In any case, the Reds are off to an okay start at 7-5 on the season. They’re in a tie with the Milwaukee Brewers for the lead in the NL Central. Head below for our free Indians vs. Reds pick on April 16, 2021.

Cleveland Indians vs. Cincinnati Reds MLB Betting Odds:


  • Indians +1.5 (-190)
  • Reds -1.5 (+165)

  • Indians +107
  • Reds -117

  • Over 9 (-110)
  • Under 9 (-110)


Indians vs. Reds Prediction:

The Indians are expected to send Logan Allen to the bump on Friday night at the Great American Ball Park. Allen earned a role in the starting rotation thanks to an impressive offseason. The former San Diego Padre made three spot appearances out of the bullpen last year for the Indians. He held up well and looked like a major league pitcher for the first time in his young career.

The 23-year-old posted an ERA of 3.38 through three outings as a reliever. That really wasn’t nearly enough for Allen to earn a spot in the rotation for this season. However, his big opportunity came in spring training where he was excellent. Allen showed tremendous improvement as a pitcher.

It’s clear from his work in spring training, he was working hard to get better in the offseason. Allen recorded an ERA of 0.64 and 0.86 WHIP through 14 innings of work. He gave up just 9 hits and 1 earned run in his time on the bump. The Padres might have given up on him too early in his career.

Allen has been in good form through two starts in the regular season. He has conceded 2 earned runs in 10 innings of work. Allen enters Cincinnati with an ERA of 2.70 and 1.20 WHIP. Not too bad for a guy that was only given three appearances out of the bullpen last season, and struggled with a 12.54 ERA in 2019 with the Padres.

Jeff Hoffman is slated to counter for the Reds on the hill. Hoffman has registered an ERA of 6.30 and 1.60 WHIP in his career, which dates back to 2016 with the Colorado Rockies. He absolutely hated pitching for the Rockies at Coors Field, and for the first time in his career, Hoffman is on a new team. Hoffman was slapped for a 9.28 ERA and 1.92 WHIP in his final season in Colorado. He didn’t have success in spring training, with a 8.50 ERA and 1.50 WHIP, so it was more of the same, picking up where left off in Denver.

So far it’s been fine for Hoffman with the Reds through a couple of starts in the regular season. Nothing spectacular, though, as Hoffman has posted an ERA of 3.86 and 1.29 WHIP in 9.1 innings of work. He is coming off an iffy performance against the Diamondbacks in Arizona. Hoffman allowed 6 hits, 3 walks, and 3 earned runs through 4.1 innings. His solid opening start against the Cardinals might have been beginner’s luck for Hoffman as a Red. It’s hard to lay juice with Hoffman as a favorite. The value is on the Indians.


Our Bet
Kyle E / Author

Kyle is a veteran of TheSportsGeek and has spent nearly a decade providing accurate sports picks and writeups here. He has been a sports handicapper for 10+ years and started sharing his picks and thoughts in 2011 at TheSportsGeek. His expertise spans across multiple sports, including the NFL, NCAAF, MLB, NHL, and horse racing. Prior to writing for TheSportsGeek, Kyle was a fantasy football expert, who ultimately parlayed it into a successful sports betting career. You can find his picks daily only at TheSportsGeek.

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