Detroit Tigers vs. Chicago White Sox Pick – MLB April 28, 2021

The Detroit Tigers and Chicago White Sox will meet again at Guaranteed Rate Field on Wednesday in Chicago. The visiting Tigers ended a five-game losing streak with a win last night over the White Sox, 5-2. Miguel Cabrera got into the act with a long ball to help propel the Tigers over Lucas Giolito. Giolito was tagged for 5 hits and 4 earned runs through 6.2 innings of work against the Tigers. It was an uncharacteristically bad performance by Giolito, as he gave up all but one of the Tigers’ runs.

Conversely, Jose Urena was solid through 7 innings with 1 earned run conceded. Urena had to work himself out of jams, but he was able to keep his composure. For the White Sox, that’s not a good performance with runners on the bases. They recorded 7 hits and 3 walks against Urena with only 1 run to show for it. That’s not good enough. The White Sox regressed to 12-10 on the season with the loss Tuesday night.

They were on a four-game winning streak, including a three-game sweep of the Texas Rangers before losing. Coming off a weekend sweep, the White Sox didn’t look too interested in beating the Tigers last night. The White Sox are two games behind the Kansas City Royals for the lead in the AL Central. They were a public darling going into this season. You could have found a lot of people high on the White Sox, but they’ve been so-so thus far. If the Lance Lynn trade is going to work out for the White Sox, they need a deep playoff run with Lynn involved in it.

He has been pitching well so far, but this was an acquisition to put the White Sox over the top, so others must step up and help. It’s just far too easy to draw conclusions, though. This is of course a marathon and not a sprint. The White Sox are expected to send out Carlos Rodon, who has been terrific this season. It’s too early to talk Cy Young, but he’s an early candidate in the American League. The Tigers will counter with Casey Mize. Mize has a lot of pressure on him as a guy expected to be the future ace in Detroit. Head below for our free Tigers vs. White Sox pick on April 28, 2021.

Detroit Tigers vs. Chicago White Sox MLB Betting Odds:


  • Tigers +1.5 (-115)
  • White Sox -1.5 (-105)

  • Tigers +181
  • White Sox -197

  • Over 8 (-102)
  • Under 8 (-118)


Tigers vs. White Sox Prediction:

Casey Mize was flying through the minor league system for the Tigers. As was expected, the former No. 1 pick in the draft was dicing up inferior competition. He was making it look far too easy. Mize has not been able to find a groove in the major leagues, though. It’s much too early to declare Mize a bust, but he has to get going. We’ve seen his ability in flashes, now some consistency must follow for the 23-year-old. He’s still really young and a lot to learn in the majors, so Tigers’ fans shouldn’t stress.

Mize goes into tonight with an ERA of 5.23 and 1.45 WHIP. He started off well this season, and there’s that flash of success I was talking about with Mize. Mize gave up only 1 earned run in his first two starts through 9 innings, but he regressed hard in his previous two showings. Against the Athletics and Royals, Mize was smoked for 11 earned runs in 9.2 innings of work. We know there’s talent there, but inconsistent pitching is a problem for him. Mize most recently allowed 7 hits and 6 earned runs against the Royals in 4.2 innings.

Through his career, Mize has posted an ERA of 6.24 and 1.47 WHIP. He has some work to do, but the promise is there. Carlos Rodon is hitting the apex of his career at 28 years old. Rodon has already thrown a no-hitter to go along with his 0.47 ERA and 0.68 WHIP. A lot of pitchers that throw a no-hitter immediately regress in the next game after going the distance, but Rodon hasn’t faltered in the least. Detroit is hitting just .199 against Rodon in 56 at-bats. He should have the upper hand on Mize in this one to lead the White Sox to a 5-3 or 5-2 victory to tie this series up at one game each.


Our Bet
Kyle E / Author

Kyle is a veteran of TheSportsGeek and has spent nearly a decade providing accurate sports picks and writeups here. He has been a sports handicapper for 10+ years and started sharing his picks and thoughts in 2011 at TheSportsGeek. His expertise spans across multiple sports, including the NFL, NCAAF, MLB, NHL, and horse racing. Prior to writing for TheSportsGeek, Kyle was a fantasy football expert, who ultimately parlayed it into a successful sports betting career. You can find his picks daily only at TheSportsGeek.

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