Houston Astros vs. Chicago White Sox ALDS Game 4 Pick – MLB October 12, 2021

The Houston Astros and Chicago White Sox are scheduled to meet on Monday after Game 4 was washed out on Sunday. Heavy rain in the area postponed the game before things got off the ground. It was a smart move to postpone the matchup well ahead of time instead of waiting out the inevitable.

The White Sox came up big in Game 3 to force a Game 4. Houston could have closed out the ALDS and advanced to the ALCS. That didn’t happen, though, as the White Sox prolonged the series with a 12-6 win. The Astros started fast in that game. They had a 5-1 lead going into the bottom of the 3rd, but that lead was quickly extinguished.

The White Sox responded with 5 runs in the bottom half of the inning to take a lead and not look back. The offense kept it coming, as they piled on more runs for a 12-6 win. Leury Garcia was the big winner of the night. He broke things open in the 3rd with a 3-run bomb to take a 6-5 lead. Garcia finished the contest with 2 hits and 4 RBIs to lead the White Sox in scoring.

Good win for the White Sox, but they can’t afford to sit back and relax now. They need another win to force a Game 5 back in Houston at Minute Maid Park. The Astros protected homefield in Houston, forcing the White Sox to need back-to-back wins at Guaranteed Rate Field to get this to a final fifth game.

Anything can happen in a Game 5. The Astros don’t want to give the White Sox any more momentum that they already have. This is a team that has to feel slightly disrespected after not getting much attention in a bad AL Central during the regular season. The AL Central didn’t have much to offer other than the White Sox.

Back to Guaranteed Rate Field on Tuesday afternoon, the Astros are scheduled to give Lance McCullers Jr. the starting nod. He might have to be close to perfect with who the White Sox have going on Tuesday. The red-hot Carlos Rodon is slated to start for the home team in this one. He’s the perfect guy for a must-win game. Head below for our free Astros vs. White Sox pick on October 12, 2021.

Houston Astros vs. Chicago White Sox Live Odds and Betting History:

The following odds are courtesy of BetOnline:

Teams Spread Moneyline Total
Houston Astros +1.5 (-198) -105 Under 8.5 (-110)
Chicago White Sox -1.5 (+173) -105 Under 8.5 (-110)
Team Data Houston Astros Chicago White Sox
Overall Record 97-68 94-71
Away/Home Record 44-38 54-28
Batting Average .268 .256
Batting Average Away/Home .265 .259
Runs Per 9 5.46 5.16
Team ERA 3.82 3.79
Team ERA Away/Home 4.09 3.56

Astros vs. White Sox Prediction:

Carlos Rodon is going into Tuesday afternoon with a hot arm. While Rodon doesn’t have much postseason experience, only one appearance last year, he has been sizzling hot since August 7.

He blanked the Chicago Cubs for a 4-0 win, and then hasn’t allowed more than 2 earned runs in an assignment in six straight starts. If we want to go further back, Rodon hasn’t allowed more than 2 earned runs in nine of his last ten outings.

Rodon has conceded 1 or fewer earned runs in four of his last six attempts. In his most recent start, Rodon went 5 innings against the Cincinnati Reds with just 1 hit allowed in a 6-1 win. Note that the White Sox have won five of their previous six games when Rodon gets the starting nod.

He appears in postseason form to be going into Tuesday. The Astros also haven’t had the best success versus Rodon. They’re hitting just .194 with 2 home runs in 103 at-bats versus Rodon. If he’s feeling comfortable on Tuesday, he should be able to neutralize the Astros’ bats.

Houston Astros vs. Chicago White Sox Betting Trends:


  • Record (Last 10): 6-4
  • 4-1 overall in their previous five games
  • 12-4 overall in their previous 16 divisional playoff games
  • 0-5 overall in their previous five games on the road
  • 0-6 overall in their previous six games on the road versus a team with a winning record
  • 1-4 overall in their previous five postseason games on the road
  • Lance McCullers Jr. ERA (Last 3): 3.50

White Sox

  • Record (Last 10): 7-3
  • 4-0 overall in their previous four games versus a team with a winning record at Guaranteed Rate Field
  • 5-1 overall in their previous six postseason games at Guaranteed Rate Field
  • 4-1 overall in their previous five divisional playoff games at Guaranteed Rate Field
  • 7-1 overall in their previous eight games versus a right-handed starter
  • 70-32 overall in their previous 102 games at Guaranteed Rate Field
  • Carlos Rodon ERA (Last 3): 2.08

Guaranteed Rate Field hasn’t been an easy place to play for opponents. The White Sox are 54-28 at home, and have had success in the postseason in their ballpark. As noted above, the White Sox are 5-1 in their previous six games in Chicago at home. Conversely, the Astros haven’t been too hot on the road this season, as they possess a record of 44-38.

Lance McCullers Jr. will need back-to-back standout performances against the White Sox. However, this time he’s going to have to do it on the road in a tough environment. McCullers posted an ERA of 3.16 and a 1.22 WHIP in 2021. He carries an ERA of 3.50 and a 1.06 WHIP in his last three starts into Tuesday afternoon.

The Astros have gone 2-2 in his last four starts, with a 6-1 win over the White Sox in Game 1. Lance Lynn struggled with 6 hits and 5 earned runs across 3.2 innings in that one. Expect Rodon to do a much better job at home in Game 4. While McCullers Jr. should be steady, the White Sox likely chip away after gaining confidence last outing. The White Sox are hitting .298 in their last ten games and should do enough here offensively.


Astros vs. White Sox Pick
Kyle E / Author

Kyle is a veteran of TheSportsGeek and has spent nearly a decade providing accurate sports picks and writeups here. He has been a sports handicapper for 10+ years and started sharing his picks and thoughts in 2011 at TheSportsGeek. His expertise spans across multiple sports, including the NFL, NCAAF, MLB, NHL, and horse racing. Prior to writing for TheSportsGeek, Kyle was a fantasy football expert, who ultimately parlayed it into a successful sports betting career. You can find his picks daily only at TheSportsGeek.

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