Minnesota Twins vs. San Diego Padres Pick – MLB July 29, 2022

The Minnesota Twins and San Diego Padres have three games at Petco Park over the weekend. Minnesota is looking to avoid a three-game skid following a 7-6 and 10-4 loss to the Milwaukee Brewers. That was a tough interleague sequence after they swept the Detroit Tigers.

The Brewers aren’t the Tigers; we know that much. The Twins continue to play mediocre baseball, with losses in five of their previous eight outings. It could be good enough to win the AL Central, though. This isn’t the toughest division in baseball.

The Twins have a two-game lead in the AL Central with a record of 52-46. That effort doesn’t deserve the lead, but the Cleveland Guardians at 50-48 don’t deserve a lead either.

This is going to be a close finish, but it could be a speedwalk between the White Sox, Guardians, and Twins. There hasn’t been a clear top contender in the AL Central, at least not so far.

The White Sox have never had the lead in the division, but could steal the division in September.

The Padres don’t have to worry about winning their division. It’s not impossible down 12 games to the Dodgers, but LA will need to start piling up on the injury report for the Padres to make a run.

San Diego is going into this series at 55-45 following three losses in four attempts. The Tigers aren’t as bad as their record suggests, but San Diego can’t lose two of three in Detroit.

Blake Snell will look to put the Padres back in the win column at Petco tonight. The Twins are expected to send promising young Joe Ryan to the mound for this one.

Head below for our free Twins vs. Padres prediction on July 29, 2022.

Minnesota Twins vs. San Diego Padres Live Betting Odds:

MLB Odds Courtesy of Bovada:
Team Spread Moneyline Total
Minnesota Twins +1.5 (-210) -105 Over 7.5 (-115)
San Diego Padres -1.5 (+175) -115 Under 7.5 (-105)
Team Data Minnesota Twins San Diego Padres
Overall Record 52-46 55-45
Away/Home Record 25-24 25-21
Batting Average .250 .237
Batting Average Away/Home .253 .221
Runs Per 9 4.66 4.35
Team ERA 3.99 3.78
Team ERA Away/Home 4.20 3.44

Twins vs. Padres Prediction:

The Twins are excited about what Joe Ryan is going to develop into on the mound. He’s already showing the potential of being a Cy Young candidate in the future. Ryan appeared in five games last season, with his true rookie campaign in 2022.

Ryan isn’t on pace for the 2022 AL Cy Young, but he isn’t that far off.

Going into the pitcher’s friendly Petco Park, Ryan owns a 2.89 ERA and 1.05 WHIP across 81 innings. He hasn’t been bothered or regressed much at all this season, either.

Ryan has been doing this pretty well all season and he’s continued to improve with experience. The 26-year-old posted an ERA of 2.20 and a 0.86 WHIP in his previous three trips to the hill.

He shouldn’t have an issue going on the road to Petco Park. In fact, he should like pitching in San Diego at this facility.

Ryan has an ERA of 2.90 and a 1.13 WHIP on the road this season.

After allowing 1 earned run in three of his last four starts, he should be in good control at Petco to open this series in this one. The Padres are a mixed bag offensively, as they’re 19th with 4.35 runs scored per 9 innings.

Minnesota Twins vs. San Diego Padres Betting Trends:


  • Record (Last 10): 4-6
  • 1-4 overall in their previous five games on a Friday
  • 1-6 overall in their previous seven games after a day off
  • UNDER is 3-1-1 in their previous five games on a Friday
  • UNDER is 7-3-2 in their previous 12 games versus a left-handed starter
  • UNDER is 5-2-2 in their previous nine games versus the NL West


  • Record (Last 10): 5-5
  • 11-2 overall in their previous 13 games on a Friday
  • 4-1 overall in their previous five first game of a series
  • UNDER is 4-0 in their previous four games veruss a starter with a WHIP better than 1.15
  • UNDER is 8-3 in their previous 11 games versus a right-handed starter
  • UNDER is 5-2-1 in their previous eight games after conceding 5 or more runs

  • Blake Snell can be better than he has been this season. That said, Snell has come up big at times and like the ace they signed from the Rays.

    That’s especially true recently, as Snell has yielded 1 or no earned runs in three of his previous four starts.

    Snell is coming off a strong performance, with 4 hits and no earned runs allowed against the New York Mets in a tough assignment at Citi Field.

    I’m looking at a low-scoring final score in this one. Maybe not a 1-0 game, but Ryan and Snell should combine to keep this game on the lower scoring side.

    Look for a 4-2 or 4-3 final score at Petco Park. The UNDER likely just makes it there in the series opener between the Twins and Padres.


    Twins vs. Padres Pick
    UNDER 7.5
Kyle E / Author

Kyle is a veteran of TheSportsGeek and has spent nearly a decade providing accurate sports picks and writeups here. He has been a sports handicapper for 10+ years and started sharing his picks and thoughts in 2011 at TheSportsGeek. His expertise spans across multiple sports, including the NFL, NCAAF, MLB, NHL, and horse racing. Prior to writing for TheSportsGeek, Kyle was a fantasy football expert, who ultimately parlayed it into a successful sports betting career. You can find his picks daily only at TheSportsGeek.

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