San Diego Padres vs. San Francisco Giants Pick – MLB April 11, 2022

On Monday night, the San Diego Padres and San Francisco Giants open a three-game at Oracle Park in the Bay Area.

A year ago, the Padres failed to deliver in a season with big expectations. They had some exciting moments with Fernando Tatis Jr., but no substance with a record of 79-83.

The Padres missed out on the postseason in the NL West, as the Dodgers and Giants dueled at the top of the division.

San Diego finished a mile behind the Dodgers and Giants, with a 28-game gap between them and the top spot. The Padres hoped to catch on with a wildcard, but even that goal proved to be too tough.

They found some success in the first series of the season, as the Padres won three of four games against the Arizona Diamondbacks. San Diego’s bats were in good form in a 10-5 win yesterday afternoon.

Caleb Smith was chased off the mound after allowing 2 hits and 4 earned runs in an inning of work. The Padres scored 5 runs in the top of the 2nd and built up an 8-0 lead in the 6th frame.

The Giants beat the Marlins in two of three attempts, with a 3-2 win yesterday to close things out in the rubber match.

Anthony DeSclafani didn’t have a great performance, with 8 hits and 2 earned runs allowed in 3.2 innings, but he escaped from suffering real damage on the scoreboard.

The tough San Francisco bullpen is off to a quick start and locked down the Marlins for just 3 hits through the rest of the game. Nick Martinez and Alex Wood are scheduled to open on the bump tonight.

Head below for our free Padres vs. Giants prediction on April 11, 2022.

San Diego Padres vs. San Francisco Giants Live Odds and Betting History:

The following odds are courtesy of Bovada:

Teams Spread Moneyline Total
San Diego Padres +1.5 (-160) +122 Over 8.5 (+105)
San Francisco Giants -1.5 (+135) -143 Under 8.5 (-125)
Team Data San Diego Padres San Francisco Giants
Overall Record 3-1 2-1
Away/Home Record 3-1 2-1
Batting Average .252 .183
Batting Average Away/Home .252 .183
Runs Per 9 5.14 3.21
Team ERA 2.83 2.89
Team ERA Away/Home 2.83 2.89

Padres vs. Giants Prediction:

The Padres will send Nick Martinez to the bump for his first appearance in the major leagues since 2017. Martinez spent four years in the majors with the Texas Rangers. That didn’t go well for Martinez, and he had to go overseas to pitch in Japan.

In his last season in the majors, Martinez posted a 5.66 ERA and 1.37 WHIP with a record of 3-8 in 2017. In four seasons across 88 games, he has a 4.77 ERA and 1.45 WHIP.

Many other pitchers get a lot more time than Martinez did to figure it out. He didn’t get much of a chance after bombing out in 2017.

Martinez was on fire with Softbank in the Japanese league last year with an ERA below 2.00. Martinez says he’s a different pitcher than he was in 2017, so we’ll see if it translates tonight.

It isn’t an easy assignment for Martinez out of the gate, as he will look to do better than veteran Alex Wood on the other side. Wood saved his career in 2021 after struggling with the Reds and Dodgers.

San Diego Padres vs. San Francisco Giants Betting Trends:


  • Record (Last 10): 3-1
  • 1-6 overall in their previous seven games versus a left-handed pitcher
  • 2-14 overall in their previous 16 games in the first game of a series
  • 1-4 overall in their previous five games after scoring 5 or more runs
  • 7-23 overall in their previous 30 games versus a team with a winning record
  • 14-37 overall in their previous 51 games as an underdog


  • Record (Last 10): 2-1
  • 60-23 overall in their previous 83 games as a betting favorite
  • 42-15 overall in their previous 57 gaems versus the NL West
  • 38-13 overall in their previous 51 games versus a right-handed starter
  • 6-1 overall in their previous seven games on a Sunday
  • UNDER is 5-2 in their previous seven games as a betting favorite

Alex Wood put his career back on track with the Giants after posting a 3.83 ERA and 1.18 WHIP. He liked pitching at Oracle Park, where Wood recorded a 3.58 ERA and 1.04 WHIP across 15 starts.

In 30 at-bats versus Wood, the Padres haven’t notched an RBI or recorded an extra-base hit. Wood isn’t scared off by this lineup, and he doesn’t have to deal with Fernando Tatis Jr. tonight at Oracle Park.

Monday night looks like a good spot for the Giants to get their third win of the season. The Giants are not the Diamondbacks, who were the worst team in the NL West last year. In a 5-3 or 5-4 win, expect the Giants to prevail.


Padres vs. Giants Pick
Kyle E / Author

Kyle is a veteran of TheSportsGeek and has spent nearly a decade providing accurate sports picks and writeups here. He has been a sports handicapper for 10+ years and started sharing his picks and thoughts in 2011 at TheSportsGeek. His expertise spans across multiple sports, including the NFL, NCAAF, MLB, NHL, and horse racing. Prior to writing for TheSportsGeek, Kyle was a fantasy football expert, who ultimately parlayed it into a successful sports betting career. You can find his picks daily only at TheSportsGeek.

Leave a Reply

Your email address will not be published. Required fields are marked *

This site uses Akismet to reduce spam. Learn how your comment data is processed.