49ers vs. Chiefs NFL Pick – Preseason Week 3

Week 3 of the NFL Preseason continues Saturday with seven games on the card. The week will conclude tomorrow night in Tennessee with the Steelers and Titans. That will be the last of “meaningful” preseason games, as by the fourth game of the preseason, everything is just about set in stone for the regular season.

The fourth game of the preseason is always the most pointless game. If anything, the coaching staff is trying to identify two or three players to make the squad as a third stringer. The NFL could be done with that preseason game and it wouldn’t make a difference, though.

The Kansas City Chiefs have seen an up and down preseason thus far. They looked like a well-oiled machine at home in the first game against the Bengals. Mahomes drove the Chiefs down the field for an early touchdown and the Chiefs rolled to a 38-17 win.

In Pittsburgh, though, the Chiefs looked out of sorts as the Steelers sliced through them for a 17-7 victory. I’m 2-0 in Chiefs game in the preseason. I was on them in Week 1 and then faded them on the road against the Steelers. Everything went accordingly, with both bets winning relatively easily.

The starters will get more action in Week 3 of the preseason. That includes Mahomes and Jimmy Garoppolo. Speaking of being out of sorts, Garoppolo looked as rusty as a beater vehicle last week. It’s to be expected for a guy who is coming off a lengthy layoff and major injury.

Don’t read too far into that performance, but I’m also not sold on Garoppolo as a franchise player. He gets a nice preseason test to bounce back in a hostile environment at Arrowhead. The starting quarterbacks will likely see the first-half and then the backups follow in the 3rd quarter. Head below for our free 49ers vs. Chiefs in Game 3 of the preseason.

San Francisco 49ers vs. K.C. Chiefs NFL Preseason Week 3 Betting Odds:


  • 49ers +3.5(-110)
  • Chiefs -3.5(-110)


  • Over 45(-110)
  • Under 45(-110)

Betting odds provided by bovada.lv

49ers vs. Chiefs Pick:

Mahomes and the starting offense for the Chiefs is going to see plenty of reps in this game. We’re not going to see anything too exotic from the Chiefs, but their offense by design is not meant to give the defense basic looks. If anything, you’re going to Mahomes slide or eat it before running down the field risking an injury. His last time on the field in KC was quite impressive. Mahomes went 4-of-4 with 66 yards and 10 yards on one rushing attempt.

Chase Litton excelled late in the game, as he passed for 122 yards with 2 touchdowns and an interception. Their defense was a standout unit as well. The Bengals’ leading rusher gained just 11 yards. If the Chiefs want success in 2019, the defense must be better than last year. There was absolutely nothing wrong with their effort against the Steelers last week, too. Josh Dobbs and Mason Rudolph both looked mediocre against the Chief defense.

It was different story for the Chiefs’ offense last week, as there was nobody on the same page. They didn’t look interested in playing against the Steelers in Pittsburgh last week. Andy Reid is an old school coach and I doubt he was happy with the effort in that contest. Expect the Chiefs look much more fluid in this contest. Mahomes is likely going to get his yardage, while on the other side, Garoppolo is still going to be shaking off the rust.

Whether it’s the preseason or not, Arrowhead is never a fun environment to go and play in. Garoppolo isn’t the only one to blame last week. The offensive line did not give him good looks. When the backups started rolling in the Niners were able to move the ball with C.J. Beathard.

The real stars of the game in the win was the backup offensive line. They were moving piles against the Broncos to open up running lames, unlike when Garoppolo was in with the starting unit. This week in Kansas City, it’s unlikely to be the case against a backup KC that have actually played very well thus far. And again, even though it’s preseason ball, Andy Reid is going to have this team looking more fluid with their heads in the game than in Pittsburgh. Look for the Chiefs by a touchdown over the 49ers on Saturday at Arrowhead.

The Bet
Kyle E / Author

Kyle is a veteran of The Sports Geek and has spent nearly a decade providing accurate sports picks and writeups here. He has been a sports handicapper for 10+ years and started sharing his picks and thoughts in 2011 at The Sports Geek. His expertise spans across multiple sports, including the NFL, NCAAF, MLB, and the NHL. Prior to writing for The Sports Geek, Kyle was a fantasy football expert, who ultimately parlayed it into a successful sports betting career. You can find his picks daily at The Sports Geek.