Buffalo Bills at Arizona Cardinals – November 15

Buffalo (7-2) at Arizona (5-3)


This is only the 12th meeting between Buffalo and Arizona as the Bills have won six out of the last seven games in the series. The lone Cardinals win in that streak was in 2008 when the Cardinals beat Buffalo, 41-17, in the desert. Buffalo won the last meeting 33-18 in 2016 in Orchard Park, N.Y. when the Bills picked off Arizona quarterback Carson Palmer four times and Bills running back Lesean McCoy had a pair of touchdown runs.


Buffalo has won three in a row after starting the season at 4-0 before a pair of losses to Tennessee and Kansas City. Bills rookie running back Zack Moss looks for his third game in a row with a rushing touchdown.

Arizona had a 3-game winning streak end last week in the 34-31 loss to Miami. Sunday’s game is also the Cardinals’ third home game in a row as they have scored 30+ points in four straight games. Arizona quarterback Kyler Murray looks for his third game in a row at home with three or more touchdown passes and he looks for his fifth in a row at home with a rushing touchdown.

Vs. The Spread

The Bills are struggling ATS at 1-4 in their last five games. That could change though as the offense has once again started to percolate. The Cardinals have gone over the total in two of the last three outings. Arizona is 5-3 ATS while the Bills are 4-5

Teams Spread Money Line Total Points
Buffalo Bills +1 (+102) +110 O 56 (-116)
Arizona Cardinals -1 (-122) -130 U 56 (-104)

Last week:

Bills quarterback Josh Allen lit up western New York with 415 yards in completing 31-of-38 passes in Buffalo’s impressive 44-34 win over the Seattle Seahawks. Allen completed seven passes over 20 yards to seven different receivers.

Arizona couldn’t solve Tua Time as Dolphins quarterback Tua Tagovailoa passed for 248 yards and led Miami on two scoring drives in the fourth quarter to give the Dolphins a 34-31 win in Arizona.

Bills Mafia

Buffalo Bills LogoAllen sees another struggling pass defense this week as Arizona has only six interceptions in it’s first eight games. Allen will be on alert for Cardinals safety Budda Baker who has a pair of picks and a pair of sacks as he is second of the team in tackles with 64. Buffalo is accruing depth behind Stefon Diggs in it’s receiving corp with John Brown and Gabriel Davis stepping forward in big ways.

Redbird Reax

Murray is a highlight reel with his dual threat abilities and will keep a below average Bills rushing defense – 26th in the NFL – on notice. He needs Kenyan Drake back in the lineup and healthy beside of Chase Edmonds as coach Kliff Kingsbury may want to feature the run even more this week. DeAndre Hopkins has 60 catches for 734 yards and will be a handful for Bill cornerback Tre’Davious White, who had his first interception last week and looks for his third straight game with a fumble recovery.

NFL Betting Predictions

Winner: Arizona (-1) 31, Buffalo 28
Over-Under: Take Over 56

The Bets
Arizona Cardinals -1
Over 56
Kenneth Cross / Author

Kenneth Cross is a new entry to The Sports Geek staff as he has 25 years of experience in print, broadcast, and internet sports journalism. Cross is a lover of all sports, but college basketball is his passion. He estimates that he has seen around 1,500 college basketball games - live and in-person - and hopes that grows this season. If you listen to Radio, you have likely heard him on Sundays covering the Carolina Panthers for some 20 years. Now in Tampa Bay, he works as a national radio correspondent.