Chiefs vs. Titans NFL Pick – Week 10

The Kansas City Chiefs with an able-bodied Patrick Mahomes in tow will fly out to Nashville for a Week 10 matchup against the Tennessee Titans. Reports indicate that Mahomes is ready to go and excited to get back on the field. He hasn’t played since suffering a knee injury against Denver Broncos on October 17th. That injury occurred early in the contest on a sneak in the red zone. Tough blow for Mahomes and the Chiefs, but they were able to survive without him that night and thereafter.

Matt Moore did a serviceable enough job to lead the Chiefs to a record of 2-1, which includes the Broncos game. His lone loss was a close affair against the Green Bay Packers on Sunday Night Football. Aaron Rodgers had to pull a rabbit out of his helmet to get a 31-24 win. Moore didn’t do anything wrong, but something was certainly missing without Mahomes on the field. The downfield potential with Mahomes at the controls was absent. Moore’s arm strength is not in the same league as Mahomes. In any event, Moore did everything asked of him in his time as the starting QB.

Andy Reid and the Chiefs hope that they don’t have to see Moore taking snaps any longer unless it’s in an epic blowout. Mahomes was on fire with 15 touchdowns and 1 interception before going down. He has racked up 2,180 yards with a tremendous 113.1 QBR. Mahomes is behind in the MVP race, but can still play catch up in November and December. There is still plenty of time for Russell Wilson to slow down while Mahomes gets right back on his fiery track.

One thing to keep in mind that Mahomes did not have a full compliment of weapons when he was healthy. He did not have the pleasure of working with Sammy Watkins and Tyreek Hill on the field at the same time. Mahomes will have a full offense to work with in Nashville. The Titans’ defense is just unlucky that they’re going to have to face the Chiefs in what will be the healthiest their skill position players have been this season. The Chiefs have been dealing with injuries on the offensive line, though, which will be the opening the Titans must exploit on Sunday. Head below for our free Chiefs vs. Titans pick on Sunday afternoon in NFL Week 10.

K.C. Chiefs vs. Tennessee Titans NFL Week 10 Betting Odds:


  • Chiefs -6.5(-105)
  • Titans +6.5(-115)


  • Over 49.5(-110)
  • Under 49.5(-110)

Betting odds provided by

Chiefs vs. Titans Pick:

Despite no Mahomes recently, the Chiefs are 2nd in the NFL with 300.7 passing yards per game. Surprisingly enough, the Falcons are 1st, but that’s because all they’re doing is throwing the ball for garbage yards from behind. The Chiefs rank 6th in the league with 390.8 yards per game and 28 points scored per game. There aren’t too many teams in the NFL who can lose their starting quarterback and still go toe-to-toe with Aaron Rodgers. While Moore gets credit for his ability to operate the Chiefs’ offense, a lot of had to do with the offense surrounding him. He had a plethora of talent to help him out, including the return of Sammy Watkins to the offense.

With Mahomes back in the saddle, the Chiefs aren’t likely to miss a beat. The Titans have provided a fairly formidable challenge defensively this season. Despite kinks on offense, the defense has kept the Titans in games. They’ve been slightly underrated with 339.4 yards allowed per contest for 13th in the league. Also note the Titans have surrendered an average of less than 20 points per contest. However, they will be without key defenders, and the Titans have allowed at least 20 points in their previous three outings. Linebacker Jayon Brown is also going to be held out for the Titans. Brown has some speed and is an asset at defending underneath routes. Mahomes should be able to exploit the Titans’ defense without his presence on the field.

The Titans will also be without a critical cog offensively, as tight end Delanie Walker won’t play on Sunday. They will also be a down an important wide receiver without Corey Davis. The Chiefs should be able to focus their attention on A.J. Brown in this one. Adam Humphries, who hasn’t found the end zone yet this season, will take on a bigger role for the Titans’ offense in Week 10. Expecting Ryan Tannehill and a banged up offense to keep up with Mahomes and company is asking a lot. Look for Mahomes to look sharp in his return to the field, as he leads the Chiefs to a win by more than a touchdown in Tennessee in Week 10.

The Bet
Kyle E / Author

Kyle is a veteran of The Sports Geek and has spent nearly a decade providing accurate sports picks and writeups here. He has been a sports handicapper for 10+ years and started sharing his picks and thoughts in 2011 at The Sports Geek. His expertise spans across multiple sports, including the NFL, NCAAF, MLB, and the NHL. Prior to writing for The Sports Geek, Kyle was a fantasy football expert, who ultimately parlayed it into a successful sports betting career. You can find his picks daily at The Sports Geek.