Detroit Lions vs. Arizona Cardinals Pick – NFL Week 3

During the second wave of NFL Week 3 action, a tale of two teams headed in different directions will unfold as the 0-2 Detroit Lions head to Arizona to take on the undefeated Cardinals.

Many pundits and football experts pegged Detroit as a ‘bet on’ side early in the year, with a lot thinking they represented excellent value to top a competitive NFC North division. Through two weeks, injuries have surfaced and they’ve already blown some big leads. Heading south to Arizona to take on Kyler Murray and his high-octane offense will certainly not be an easy task.

For the Cardinals, the vision of head coach Kliff Kingsbury finally seems to be taking shape. Kyler Murray looks to be in the early conversation for league MVP, and improvements to the squad’s defense have made this group a real contender in the NFC West.

While it seems as if this game is pretty cut and dry even before kick-off, the NFL does bring out some wacky results. Though the Cards are cruising right now and look absolutely elite compared to the depleted Lions, let’s not forget that Detroit has some talent themselves. Two weeks does not change that much, and after all – that is why we play the games. Alright, enough with the cliches – let’s move onto the picks! Read on beneath the odds for this Lions/Cardinals showdown to find out who we are liking in this crucial Week 3 match-up. Enjoy the game!

Detroit Lions vs. Arizona Cardinals Betting Odds:

Detroit Lions +6 (-110)
@ Arizona Cardinals -6 (-110)

Over 55.5 (-110)
Under 55.5 (-110)

*Betting odds provided by

Detroit Lions vs. Arizona Cardinals Pick:

Let’s be clear from the outset, this really isn’t a good time for Detroit to be missing two of their top three cornerbacks. Kyler Murray and DeAndre Hopkins have quickly built a solid passing rapport, and the offense for Arizona has been elite so far.

The pace in which the Cardinals play is also a cause for concern. Arizona has quickly had defenses huffing and puffing in the early stages through two weeks. They move the chains and run right up to the line of scrimmage. The Lions need to be ready for how fast this attack comes at defenses. Nobody is expecting them to shut down the Cards, but if they can limit Murray enough – it can give a talented Detroit offense enough of a shot to keep things tight.

Through two weeks, Detroit has blown big leads to key divisional opponents. Not a good look by any stretch, and it puts all kinds of pressure on their offense to seek out some positive results here in Week 3. Fortunately for Detroit, they finally will get back their number one receiver in Kenny Golladay. When the Lions’ passing attack is at full strength it can be one of the best in the NFL, and they should really test Arizona’s secondary here in Week 3.

Detroit is also getting back Halapouli Vaitai along the offensive line, which should add to Matt Stafford’s comfort level when dropping back into the pocket. With added protection, he should be able to keep the chains moving – especially through the air. The Lions have both Golladay and Marvin Jones Jr. that can really trouble an unproven Cardinals’ defense, and expect them to do just that on Sunday.

While Detroit is going to struggle to hold Murray off with regularity, I’m equally confident that the Cardinals will also struggle to keep Matt Stafford and the Lions’ attack off of the board. This should be a high-scoring affair, but ultimately one in which Detroit does enough to keep things tight throughout. Despite a frustrating 0-2 record and many blown leads already, it’s a long season and the Lions can and will find a road back. Expect that to start for them in Week 3.

My Pick
Lions +6
Will S. / Author

Will has been working with The Sports Geek since its early days back in 2010. He began as a soccer specialist, focusing on detailed reports for major international competitions, including the World Cup and European Championships. Since then, he has produced weekly pick articles on both the NFL and English Premier League, while also contributing blog posts on the NHL, MLB, and even WWE wrestling. Will is also an avid sports bettor and daily fantasy player, always eager to share his thoughts and insight on anything going on in the world of sports.