Houston Texans vs. Arizona Cardinals Pick – NFL Week 7

The Houston Texans are looking for the biggest upset of the season with a win over the red-hot Arizona Cardinals. This is a tough spot for the Texans, but that’s why they call them upsets. The Texans are going into this one with a record of 1-5 after a 31-3 loss against the Indianapolis Colts last week.

They were empty following a 25-22 loss against the New England Patriots the week before. That was a hard-fought contest for the Texans, who had nothing to offer at Lucas Oil Stadium versus the Colts. Prior to their close call against the Patriots, the Texans were stomped on for a 40-0 final versus the Bills in Buffalo.

They do have a win this season, though this was against Trevor Lawrence and the Jaguars. Keep in mind that this was his first ever start. It was also Urban Meyer’s debut as a head coach in the NFL. The Texans were able to take advantage with a 37-21 win. Since then, the Texans have lost by 10, 15, 40, 3, and 28 points.

Davis Mills will have another chance in the starting role in the desert. If anything, Mills has proven that he can be a very good backup in the NFL. He’s looked like a raw rookie thus far that has the potential to be a starter. Worst case scenario, Mills has earned a job as a backup in the future at a minimum.

Is he going to be able to keep pace with Kyler Murray? Probably not, but the bigger question is if he can keep this game within the number. This is a big number with two touchdowns and more than a field goal to cover. The Cardinals have cruised past some good teams this season, including the Rams, 37-20, Titans, 38-13, and Browns, 37-14.

They are coming off an impressive road trip to Cleveland. The Cardinals breezed past the Browns for a 37-14 win on the road. Murray passed for 229 yards and 4 touchdowns. He has looked more confident standing in the pocket and going through his progressions this season.

Murray had a knack for taking off and running too soon. He’s standing firm in the pocket and waiting for an option before using his legs. Murray is backed by a strong defense that has been providing the offense with good starting field position. Head below for our free Texans vs. Cardinals pick on October 24, 2021.

Houston Texans vs. Arizona Cardinals Live Odds and Betting History:

The following odds are courtesy of BetUS:

Teams Spread Moneyline Total
Houston Texans +18 (-110) +900 Over 47.5 (-110)
Arizona Cardinals -18 (-110) -1600 Under 47.5 (-110)
Team Data Houston Texans Arizona Cardinals
Overall Record 1-5 6-0
ATS Record 3-3-0 5-1-0
Away/Home Record 0-3 2-0
ATS Away/Home 1-2-0 1-1-0
Points Per Game 15.3 32.3
Points Against Per Game 28.7 18.2
Passing Yards Per Game 207.2 272.3
Rushing Yards Per Game 87.2 130.7

Texans vs. Cardinals Prediction:

Davis Mills has passed for 912 yards, 5 touchdowns, and 7 interceptions on 63.3% completions. With what Mills has to work with in Houston, I can’t criticize him too harshly.

He has Brandin Cooks, who is being dangled as tradebait right now, but other than that Mills is left out to fend for himself. Cooks led the Texans again last week, this time with 89 yards on 9 receptions.

The Cardinals should be able to put the clamps down on a Houston offense that is averaging 294.3 yards per game for 29th in the league. They’re worse at putting points on the board, with only 15.3 points per game.

After scoring 37 points in the season-opener, the Texans have scored more than 21 points only once in a 25-22 loss versus the Patriots.

They’ve scored an average of 11 points per game since Week 2. Improving on that could be difficult in Arizona.

The Cardinals are tenth in the league with 342.8 yards against per game. They’ve been tough to pass on, with 214.8 yards allowed per game for sixth.

Hammering the ball on the ground to help Mills out likely won’t work versus this front. It’s going to force Mills to fire away on 3rd and long often against a quality Arizona secondary.

Houston Texans vs. Arizona Cardinals Betting Trends:


  • 3-8 ATS in their previous 11 games versus a team with a winning record
  • 1-4 ATS in their previous five games in October
  • 1-5 ATS in their previous six games in Week 7
  • 1-4 ATS in their previous five games versus the NFC
  • 0-5 overall in their previous five games on the road


  • 5-1 ATS in their previous six games
  • 6-0 overall in their previous six games
  • 4-1 ATS in their previous five games versus the AFC South
  • 6-0 ATS in their previous six games in October
  • OVER is 6-2 in their previous eight games

Kyler Murray is looking to improve on 14 touchdowns, 4 interceptions and a 73.8 completion percentage. He’s also gained 116 yards and 3 touchdowns on 3.8 yards per carry. This is a well thought out offense with depth.

The front office did a good job surrounding Murray with talent from the No. 1 guy in DeAndre Hopkins, to somebody like Christian Kirk and A.J. Green who are excellent secondary options. The Cards are fourth in the NFL with 32.3 points per game, and an average of 403 yards.

The Texans’ offense has been bad, and the defense isn’t stepping up either. They’ve conceded 391.2 yards and 28.7 points per game, which both measure near the back of the league. This is a lot of points, but it doesn’t look like a good spot for Houston.

The Cardinals pulling away for a 38-13 win doesn’t look unrealistic. Expect Mills to try and play keep up with Murray. It’s likely not going to go well, with the Cardinals taking over on short fields frequently. I like the Cards by more than 3 touchdowns.


Texans vs. Cardinals Pick