Los Angeles Rams vs. Arizona Cardinals Week 14 MNF Pick – December 13

A huge divisional showdown in the NFC West will be the Week 14 edition of Monday Night Football as the 8-4 Los Angeles Rams look to regain their form by taking on a tough 10-2 Cardinals squad at State Farm Stadium.

At the start of the season, few would have thought that the Cardinals would have a two-game lead on the Rams, but Arizona has put together an impressive season. They’ve endured injuries to Kyler Murray and DeAndre Hopkins, and their defense has really stepped up in 2021.

The Rams are at a bit of a crossroads right now. Though they started the year quite hot, losing Robert Woods has really taken away a needed element from their offense. It doesn’t help that Matt Stafford is clearly banged up at quarterback either, while new additions like Von Miller and Odell Beckham Jr. haven’t paid off just yet.

This is very much a measuring stick match for both teams, and one that should have heavy playoff implications down the line. It’s not often we get to finish the week with such a classic encounter, but Rams/Cards certainly has the makings for one!

For added insight on this big-time clash, live odds, trends, and the latest data – keep reading below for our betting analysis on this NFC West divisional clash, as we look to stay hot following an undefeated Week 13. Enjoy LA vs. Arizona, folks!

Los Angeles Rams vs. Arizona Cardinals Live Odds & Betting History

*These odds are provided by BetOnline.ag


  • Los Angeles Rams +2.5 (-110)
  • Arizona Cardinals -2.5 (-110)

  • Los Angeles Rams (+115)
  • Arizona Cardinals (-135)
Total Points:

  • Over 51.5 (-110)
  • Under 51.5 (-110)
Overall Record 8-4-0 10-2-0
ATS Record 5-7-0 9-3-0
Home/Away Record 4-2-0 3-2-0
Points Per Game 28.0 28.6
Points Against Per Game 22.7 18.7
Passing Yards Per Game 289.0 244.6
Rushing Yards Per Game 100.4 113.7

Los Angeles Rams vs. Arizona Cardinals Prediction

One of the best things to date about this impressive Cardinals season has to be that they gave both DeAndre Hopkins and Kyler Murray three games off in the middle of the season, and this group didn’t really miss a beat. Now, with Murray and Hopkins healthy and back in the fold, this is once again a rejuvenated attack. Kyler Murray looked his usual agile self last time out, scrambling all over the Bears’ defense and moving the chains with his feet.

Last time the Cards played the Rams, Murray torched them with ease – both through the air, and mostly with his legs and elusiveness. L.A. has since gone out and acquired Von Miller, but limited viewings of the veteran in a Rams jersey haven’t produced the performances we’ve come to expect from the former Bronco.

Downfield Murray will look to avoid Jalen Ramsey, and that could somewhat nullify Hopkins. That said, this is a loaded passing attack and the Cards are definitely primed to take advantage of this Rams’ secondary. All of Zach Ertz, Rondale Moore, Christian Kirk, and AJ Green should have matchup advantages, and this Cardinals’ offense is poised to make this Rams’ stop unit work on defense.

Meanwhile for the Rams, it’s going to be interesting to see if they can keep pace with Arizona. Since losing Robert Woods, their offense hasn’t been the same. They’ve had issues implementing Odell Beckham into the fold, and Arizona seems well-suited to limit what they do. Last game, Byron Murphy blanketed Cooper Kupp and without many other playmakers to focus in on, you’ve got to think if Arizona can limit Kupp, it’ll be tough for Stafford to find other options in his current state.

Los Angeles might look to run the ball, though Darrell Henderson remains iffy to suit up. Arizona has lost JJ Watt from their defensive line, so look for a heavy workload for Sony Michel. That said, if the Rams trail early, how much running will Sean McVay want to commit to?

Cardinals vs. Rams Trends To Know:

  • Rams are 1-5 ATS in their last 6 games overall.
  • Rams are 0-7 ATS in their last 7 games following a straight up win of more than 14 points.
  • Cardinals are 4-0 ATS in their last 4 vs. NFC West.
  • Cardinals are 8-2 ATS in their last 10 games overall.
  • Favorite is 8-1-1 ATS in their last 10 meetings.


The injury report leans Arizona’s way and the game script should too.  They’re the healthier and hungrier squad at the moment, and their offense can beat Los Angeles in too many ways.  Matt Stafford is clearly still banged up, and asking him to do too much against an impressive Cardinals defense won’t be a good idea.  At home, Arizona as a small favourite makes a lot of sense.

My Pick
Cardinals -2.5
Will S. / Author

Will has been working with The Sports Geek since its early days back in 2010. He began as a soccer specialist, focusing on detailed reports for major international competitions, including the World Cup and European Championships. Since then, he has produced weekly pick articles on both the NFL and English Premier League, while also contributing blog posts on the NHL, MLB, and even WWE wrestling. Will is also an avid sports bettor and daily fantasy player, always eager to share his thoughts and insight on anything going on in the world of sports.

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