Week 10 Monday Night Football DFS Picks at FanDuel

Week 10 in daily fantasy football wraps up on Monday Night Football, where the San Francisco 49ers host the New York Giants. From a pure fan perspective, this is a pretty meaningless football game with neither the Giants or Niners having a shot at making the playoffs this year.

There is a lot to consider for fantasy football, though, and with FanDuel’s one-game showdown contests, you can win some cash if you piece together the right plays from this duel.

Keep in mind there is some mild concern about this game being moved or delayed due to the fire situation going on in California, but for now the game should go off without a hitch.

I don’t have a ton of confidence in either of these teams, but the 49ers are at home and have a way better offensive system. I’m leaning towards using the Niners, but I do like the idea of just balancing this lineup out. Here are my favorite NFL DFS picks for Monday’s game:

MVP (1.5x points): Nick Mullens, QB, San Francisco 49ers ($15k)

Obviously Mullens is not the top stud to target in this game. If you want to just play it safe, then Saquon Barkley or Odell Beckham Jr. are your best bets. But most NFL DFS lineups will feature one of those guys in this slot, so the more GPP-ish play may be to double-down on Mullens.

He’s not a safe play by any means, but the Southern Miss product looked quite good in his first NFL start a week ago and has shaded of Brett Favre to his game. It’s no coincidence that they hail from the same school and don the same number on their jersey, I’m sure. Still, the kid looks like a player and based on Kyle Shanahan’s awesome system, I think he’s worth a roll of the dice here.

Mullens will be at home and faces a regressing Giants defense that ranks just 19th against fantasy passers over the last four weeks. It’d be so Giants to let him tear it up tonight and I think he does just that.

FLEX: Saquon Barkley, RB, New York Giants ($17k)

While I love Mullens, I have to roster New York’s studs. The 49ers still aren’t elite defensively and will give up some production in this game. Barkley has been a DFS monster all year throughout his rookie campaign, registering 15+ fantasy points in every single game he’s played.

He’s about as safe of a play as is available on this slate, but San Francisco has actually been respectable against the run in terms of rushing yardage allowed. That’s one reason why I’ll slide Barkley out of the MVP slot, but I still think he’s a great play anywhere on your one-game NFL DFS roster.

FLEX: Odell Beckham Jr., WR, New York Giants ($16k)

Talent and volume make Odell a necessity tonight. The Niners are a bottom-12 unit against fantasy wide receivers anyways, but this is a guy who sees 10+ targets weekly and has that home run ability every time he touches the football.

Beckham has been a drama queen for the G-Men, but he’s still a huge offensive talent in a good spot on prime-time television. He’s not my MVP for this contest, but I wouldn’t argue strongly against it if that’s the route you take tonight.

FLEX: Trent Taylor, WR, San Francisco 49ers ($6k)

I am willingly fading the likes of Eli Manning, Sterling Sherpard, George Kittle, Evan Engram, Marquise Goodwin and Matt Breida. All of those options are plenty fine, but I want the top two studs and I also love Mullens tonight.

I think I can get by with some value and Taylor could be part of it. He has not seen much work lately, but he had a big game just three weeks ago and Pierre Garcon (knee) won’t play tonight. With New York probably focusing on stopping the run and containing Goodwin deep down the field, I’m banking on Mullens finding guys in the intermediate and short passing game more tonight.

FLEX: Kendrick Bourne, WR, San Francisco 49ers ($6k)

That should also include Bourne, who is a direct benefactor to Garcon being out. He’s stepped up lately, scoring in week nine and turning 10 targets into seven grabs two weeks ago. He’s no star, but the 49ers system works and if I like Mullens, I have to like some of his weapons.

The top San Francisco weapon is George Kittle, but New York ranks 9th at stopping tight ends. It’s possible the Niners will have to get creative and get other guys involved through the air. Hopefull that ends up being Taylor and Bourne.


I’m not really playing around on this slate. I’m rostering the two more explosive fantasy options, banking on Mullens duplicating what he did a week ago and hoping New York can take away San Francisco’s two top passing game threats. If so, this could be a fun night.

Disagree? Considering sliding Beckham or Barkley into the MVP slot and dropping from Mullens to balance things out more. Personally, I love him in this game and think he’s a very nice play (and hopefully contrarian) at the MVP spot.

Whatever you decide, hopefully I helped you in some way tonight. Good luck and enjoy the game!