Finding the Thursday Night Football best bets this week can be tricky, but our team is here to help! We will share our analysis and expert predictions throughout the entire NFL season, including recommended TNF player props.
In one of the biggest primetime matchups this season, the Los Angeles Rams and Seattle Seahawks get Week 16 started in a crucial primetime matchup for both clubs. Check out our Thursday Night Football predictions and top picks in Washington at Lumen Field.
TNF Best Bets This Week: Rams vs. Seahawks (Snapshot)
Thursday Night Football Odds and Betting Lines for Week 16
The best NFL betting sites have a slew of Week 16 Thursday Night Football odds available for wagering in the Rams vs. Seahawks matchup. The main markets, including the point spread, are on the board at most major sportsbooks.
Let’s delve into the Rams vs. Seahawks lines and best Thursday Night Football bets below! The following TNF odds for Week 16 are courtesy of Lucky Rebel:
| TEAM | SPREAD | MONEYLINE | TOTAL |
|---|---|---|---|
| LA Rams | -1 (-110) | -119 | Over 44 (-110) |
| Seattle Seahawks | +1 (-110) | -102 | Under 44 (-110) |
The Los Angeles Rams (-119) are slight favorites on the road against their NFC West rivals. As -119 favorites on the favorite, the Rams have a 54.3% implied probability to win outright. With nearly even odds, online bookies are projecting a close game that goes to the wire.
The Rams only have a one-point advantage on the point spread, so there isn’t much consensus among oddsmakers. They are favored to win Super Bowl 60 and would receive another boost in their price with a win on Thursday night. At 44 points, the matchup is expected to be a physical, defensive battle.
If you are interested in alternative lines and unique TNF prop bets tonight, Lucky Rebel has a wide selection of options. You can find the most up-to-date TNF betting odds at Lucky Rebel by navigating to Sports > Football > NFL > Rams vs Seahawks.
Thursday Night Football Betting Trends
There are some key betting trends to keep in mind before placing your best Thursday Night Football bets!
I’ve dug through several trends for this matchup and have isolated the best to consider for the Rams vs. Seahawks matchup:
- The Los Angeles Rams are 7-2 against the spread (ATS) in their previous nine matchups.
- The Los Angeles Rams are 9-2 against the spread (ATS) in their previous 11 games on the road.
- The Los Angeles Rams are 4-1 against the spread (ATS) as a favorite on the road in 2025-26.
- The Seattle Seahawks are 7-2 against the spread (ATS) in their previous nine matchups.
- The Seattle Seahawks are 5-0 against the spread (ATS) in their previous five games versus the NFC.
- The Seattle Seahawks are 5-1 outright in their previous six matchups at home.
- The OVER is 4-2 in the Los Angeles Rams’ previous six matchups.
- The UNDER is 5-1 in the previous six games between the Los Angeles Rams and Seattle Seahawks.
TNF Football Prediction and Betting Pick: Rams vs. Seahawks
The Rams (11-3) and Seahawks (11-3) meet with the NFC West lead on the line. With the Rams winning the first matchup at SoFi Stadium, 21-19, they currently own the tiebreaker. However, a Seahawks win would give them sole control of the division with only two games remaining.
Seattle is seeking revenge after that two-point loss in mid-November. It was a horrid performance from Seahawks QB Sam Darnold, who threw four interceptions in his worst start of the season. If Darnold had simply played a mediocre game instead of a terrible one, the Seahawks probably would have won that matchup.
Last week, the Seahawks survived a trap spot, edging the Indianapolis Colts 18-16 on six Jason Myers field goals. With 44-year-old Philip Rivers under center for Indy, Seattle clearly looked past its opponent and ahead to this Week 16 showdown with the Rams. Meanwhile, Los Angeles prevailed in a track meet against the Detroit Lions, 41-34.
The Rams’ offense was on fire again, but could they be in for a letdown in Seattle? They had to empty the tank offensively to outlast a Lions offense that never allowed them to rest.
While the Rams’ attack is unlikely to be fully neutralized, that taxing effort may give the Seahawks a small edge against a potentially fatigued unit. Seattle’s defense is tough under any circumstances, but the schedule spot doesn’t favor the Rams.
Head coach Mike Macdonald has transformed the Seahawks into one of the most respected defenses in the league. Overall, Seattle ranks fourth in the NFL, allowing just 283 yards per game. The Seahawks give up only 91.6 rushing yards and 191.4 passing yards per game, both among the best marks in the league. They are also fourth in sacks, with three recorded per game.
Nick Emmanwori genuinely does EVERYTHING for the Seahawks defense:
— NFL Draft Files (@NFL_DF) December 7, 2025
– 6 tackles
– 2 TFLs
– 1 sack
– 1 QB hit
– 1 PBU
– 1 INT
– 1 blocked field goal
Who let Mike Macdonald get this absolute monster…. pic.twitter.com/GpJr1sGhz0
In a big primetime spot, expect Ernest Jones and Nick Emmanwori to make their presence felt up front against the Rams. While the defense should do enough to disrupt Los Angeles, Darnold is also poised to bounce back after that awful first meeting. The Rams rank only 19th against the pass, surrendering an average of 219.7 yards per game through the air.
Since that initial matchup, Darnold has thrown five touchdown passes and just one interception over four games. Expect his top target, WR Jaxon Smith-Njigba, to deliver a big performance. He’s the favorite to win NFL Offensive Player of the Year, and I expect him to all but clinch the award in Week 16.
Given all that, I recommend backing the Seahawks as one of your best Thursday Night Football picks.
Team TNF Prop Bets: Falcons vs. Buccaneers
Leading online bookmakers Bovada and Lucky Rebel have various Thursday Night Football prop bets for the Rams vs. Seahawks. Let’s delve into my top team props to open Week 16:
Winning Margin: Seahawks by 1-6 Points (+270)
The oddsmakers got this one right, with the Week 16 TNF odds nearly even. The trends all point to this matchup being a closely contested game at Lumen Field. However, I believe the wrong team is favored on Thursday night.
The Seahawks have the advantage on a short week, even if their edge is not big. They were already able to look ahead to the Rams in Week 15, while Los Angeles didn’t have that luxury against the Lions. It’s also always a special game for Matthew Stafford when he faces his former team.
The Seahawks were a field goal away from beating the Rams in Los Angeles. They’ve already shown they can contain Stafford, who threw for only 130 yards in that game.
I expect the pass rush to get home and force Stafford into mistakes in Seattle. The Seahawks lead the NFL with an average win margin of +11.6 overall and +11.7 at home.
I’m picking the Seahawks to win by a field goal, so the winning margin prop of one to six points is a bet worth considering.
Both Teams Score 17 Points: Yes (-135)
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- Yes (-135)
- No (+105)
Although I mentioned that the Seahawks’ defense is set to make plays in this game, it’s unlikely the Rams will be held to fewer than 17 points. If the Seahawks hold the Rams to 20 points, it would be a strong effort for their defense.
The Rams rank second in the NFL, with 30 points scored per game. They’ll put some points on the board despite the Seahawks coming up big at times. Meanwhile, Darnold is in for a bounce-back game after he struggled in his last outing versus the Rams.
Even then, the Seahawks still managed to score 19 points after Darnold threw four interceptions. Overall, the Seahawks have notched 28.9 points per game and have one of the most underrated offenses in football. In short, yes, both teams will score 17+ points, so this is an attractive option for your best TNF prop bets.
Best Thursday Night Football Player Props This Week
In addition to team props, consider adding a few TNF player prop bets to your Rams vs. Seahawks card! There are a few plays that have caught my attention, so let’s analyze these Thursday Night Football picks below.
Anytime Touchdown: Zach Charbonnet (SEA) (+145)
Seahawks’ RB Zach Charbonnet presents strong value as an anytime touchdown bet tonight. Charbonnet is the more physical and rugged running back between him and Kenneth Walker. He regularly takes carries away from Walker in the red zone and gets touches for touchdowns.
Charbonnet and Walker often split carries as well, so the value at +145 is worth a look here. The Seahawks’ running back has rushed for 514 yards and eight touchdowns through 13 games this season. He’s scored five touchdowns over the Seahawks’ previous eight games.
Zach Charbonnet adds to the @Seahawks massive first half lead.
— NFL (@NFL) November 9, 2025
AZvsSEA on CBS/Paramount+https://t.co/HkKw7uXVnt pic.twitter.com/ioUcrZrlm1
The former UCLA running back recorded eight touchdowns in 17 games last season. He’s well on pace to eclipse that number and can certainly hit nine touchdowns on the season with a big score against the Rams. For your best Thursday Night Football props this week, consider Charbonnet at +145.
Anytime Touchdown: Blake Corum (LAR) (+270)
On the other side, circle Rams’ RB Blake Corum for a massive value play to score a touchdown at +270 odds. The way I see it, Corum should have closer to +170 on his anytime touchdown price.
#Rams Blake Corum over his last 3 games:
— SCOUTD (@scoutdnfl) December 15, 2025
📌 280 rushing yards
📌 4 rushing TDs
📌 9.3 yards per carry
The former 3rd round pick is quietly turning into a star for LA 🌟 pic.twitter.com/1waRIqnmyw
Corum has taken on a larger role in the offense recently and is taking advantage of the opportunities. In his second year in the NFL, Corum has established himself as a leading back. He and Kyren Williams provide a strong 1-2 punch, with Corum getting more carries recently.
The Michigan alum has rushed for 280 yards and four touchdowns over the last three games. Like Charbonnet, he’s a physical runner who can put his head down and find the end zone. The value is too good to pass up on at +270. Back Corum as one of the best TNF player props tonight.
Total Receiving Yards: Jaxon Smith-Njigba (SEA) Over 89.5 (-120)
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- Over 89.5 (-120)
- Under 89.5 (-110)
Seahawks WR Jaxon Smith-Njigba has cemented himself as one of the most dangerous weapons in the NFL this season. “JSN” continues to produce and has overtaken Jonathan Taylor as the clear frontrunner for OPOY.
Smith-Njigba has recorded 1,541 yards, nine touchdowns, and 96 receptions in 2025-26. He’s coming off yet another 100+ yard performance, his ninth of the season. The former Buckeye standout should be in for another elite showing against the Rams on Thursday night.
Jaxon Smith-Njigba has 9⃣ games with 100+ receiving yards (most in the NFL) ✅@Seahawks | #GoHawks pic.twitter.com/A4Gny2U0g2
— NFL+ (@NFLPlus) December 15, 2025
The Rams’ secondary is one of this team’s biggest weaknesses. They rank in the back half of the league and are prone to giving up big plays. This sets up perfectly for Smith-Njigba. Week 16 at home is the biggest stage he’s had this season, and I don’t expect him to slow down.
Before finalizing your Thursday Night Football player prop bets, consider taking Smith-Njigba over 89.5 receiving yards.
Thursday Night Football Parlay for Week 16
To wrap up your TNF betting card, consider adding a parlay to your selections because there is strong value on the three player props at Lucky Rebel.
In short, I recommend Charbonnet anytime TD, Corum anytime TD, and Smith-Njigba over 89.5 receiving yards in a parlay. If all three bets hit, there is a huge payout awaiting at +1562 odds!
- Charbonnet: Anytime Touchdown
- Corum: Anytime Touchdown
- Smith-Njigba: Over 89.5 Receiving Yards
Thursday Night Football Betting Summary: Rams vs. Seahawks
The Sports Geek is excited for the Week 16 card with our best Thursday Night Football bets for the Rams vs. Seahawks! Do you like the TNF predictions?
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