The Heisman odds for 2025 initially favored Arch Manning, but that feels like an eternity ago! The hectic college football season produced a battle between two other quarterbacks that might’ve been decided in a single game recently.
We’re about to find out soon, as the ceremony is on Saturday, December 13. I’ll take a look at the top two favorites after Championship Week, as well as a darkhorse (and former favorite) before sharing my Heisman prediction at the end of this article!
2025 Heisman Trophy Winner Odds
Here are the Heisman winner odds, courtesy of Lucky Rebel:
| PLAYER | ODDS |
|---|---|
| Fernando Mendoza (Indiana) | -2200 |
| Diego Pavia (Vanderbilt) | +1100 |
| Jeremiyah Love (Notre Dame) | +30000 |
| Julian Sayin (Ohio State) | +50000 |
| Jacob Rodriguez (Texas Tech) | +50000 |
| Jeremiah Smith (Ohio State) | +50000 |
| Gunner Stockton (Georgia) | +50000 |
Fernando Mendoza (-2200) has taken full control of the Heisman betting race at the best college football betting sites! The Indiana star has an implied probability of 95.6% to win the award after leading the Hoosiers to the #1 seed in the CFP Playoffs and their first-ever #1 AP Poll ranking. He was +185 and second in the Heisman odds, heading into the Big Ten title game.
Vanderbilt’s Diego Pavia (+1100) is the closest challenger to Mendoza with an implied probability of 8.3%. It’s a big drop from last week when Pavia was +175.
Then you have a group of darkhorses, such as Notre Dame’s Jeremiyah Love (+30000), Georgia’s Gunnar Stockton (+50000), and Texas Tech’s Jacob Rodriguez (+50000). Love is probably the best of this group, but the Fighting Irish won’t play again this season. They’ve opted out of a bowl game after being snubbed for a CFP Playoff spot.
The Ohio State duo of Julian Sayin (+50000) and Jeremiah Smith (+50000) are also included. Sayin was the favorite in the 2025 Heisman odds at +170 very recently, but losing to Indiana in the Big Ten title game was a massive blow to his chances.
You can wager on the updated Heisman odds at Lucky Rebel by going to Sports > Football > NCAA Football Futures > Heisman Trophy.
The Favorite in the 2025 Heisman Odds
First, let’s examine the 2025 Heisman odds for the favorite going into the CFP Playoffs!
Fernando Mendoza (-2200)
Mendoza did just enough to help Indiana to a 13-10 win over Ohio State in the Big Ten championship game, going 15-of-23 for 222 yards, a touchdown, and an interception. A third-quarter 17-yard touchdown pass to Elijah Sarratt sealed the deal for Indiana in a defense-first matchup.
HEISMENDOZA 🏆
Fernando Mendoza put up a legendary performance in the Big Ten Championship 😤 pic.twitter.com/EcdzllaLar
— FOX College Football (@CFBONFOX) December 7, 2025
The junior quarterback wasn’t incredible, but he made the plays the team needed. Mendoza will enter the CFP Playoffs with 2,980 yards, completing 71.5% of his passes, with 33 touchdowns and six interceptions. The Hoosiers earn a bye with the top seed, and will play the winner of Alabama-Oklahoma in a quarterfinal Rose Bowl.
The voters will also look at Indiana’s 13-0 record, which gives Mendoza a considerable edge in the Heisman betting odds. That’s why you’ll find him at -2200, which, I think, is a bit overpriced. But his team is the #1 squad in the country, and it’s tough to argue against that!
The Top Contender in the 2025 Heisman Betting Odds
One player is trying to stay within striking distance of Mendoza in the Heisman race!
Diego Pavia (+1100)
Pavia didn’t play last weekend as the Commodores finished 10-2, and they missed out on the CFP Playoff. Vanderbilt, instead, will play Iowa in the Reliaquest Bowl on New Year’s Eve. He tried his best, however, as Pavia asked President Donald Trump to expand the playoff to 16 teams.
Diego Pavia is calling on President Donald Trump to sign an executive order expanding the College Football Playoff to 16 teams pic.twitter.com/JY6CGlCZk3
— Bussin’ With The Boys (@BussinWTB) December 3, 2025
The senior signal-caller completed 71.2% of his passes for 3,192 yards, 27 touchdowns, and eight interceptions. He also ran for 826 yards and nine scores, far more than Mendoza and Sayin. Does the fact that the Big Ten quarterbacks are in the playoff, and Pavia isn’t, matter that much?
I believe Pavia has a shot, since neither quarterback had a great Big Ten title game. Pavia played in, arguably, a tougher conference. He has comparable passing numbers, and has doubled the combined rushing yards of Mendoza and Sayin. At +1100, why not take a chance on a Pavia Heisman betting return?
Best Longshot Heisman Odds for 2025
This darkhorse has been atop the Heisman odds all season. Can he provide a massive return for you?
Julian Sayin (+50000)
Sayin wasn’t bad in the Indiana-Ohio State game, going 21-of-29 for 258 yards, a touchdown, and an interception. He hooked up with fellow Heisman candidate Jeremiah Smith eight times for 144 yards. The difference may have been Sayin coming up short on a third-quarter 4-and-1 on the Indiana 5-yard-line.
Julian Sayin was SHORT pic.twitter.com/t0Skt2Hbcy
— Unnecessary Roughness (@UnnecRoughness) December 7, 2025
I don’t think Sayin should be priced this high in the Heisman odds. He should be closer to Love (+30000), if not ahead of him. But he’ll finish with 3,323 yards, 31 touchdowns, and six picks. He also led the nation in completion rate at 78.9%, which was the highest regular-season mark in history.
It’s a tough break for the sophomore quarterback, who will likely return to Columbus next season, alongside Smith. The duo will probably be among the Heisman betting favorites, and the Buckeyes will be high, if not atop, the college football championship odds.
But this will sting for Ohio State, who did take the #2 seed in the CFP Playoff. They will play the winner of Miami-Texas A&M in a quarterfinal Cotton Bowl game after a bye.
2025 Heisman Trophy Prediction and Betting Pick
At this point of the season, it’s safe to expect that the winner won’t come from one of the top three.I’m leaning towards Fernando Mendoza for my 2025 Heisman betting prediction, but at -2200, there’s no value in his odds.
Instead, I’m going to place a small wager on Diego Pavia at +1100! Vanderbilt’s two losses came on the road against Alabama and Texas. The Crimson Tide are in the CFP Playoff, while Texas just missed out. He wasn’t good in the Alabama game, but Pavia lit up Texas for 365 yards and three touchdowns with no picks.
It’s just a matter of how much getting to the playoff matters to the voters, and I believe that’ll lean that way. But I’m poised to grab the value at +1100 if Pavia takes advantage of an average Big Ten title game for both Mendoza and Sayin. Let’s go with Vanderbilt’s Diego Pavia at +1100 in our 2025 Heisman picks!
Where to Bet on 2025 Heisman Odds?
You can wager on Pavia’s Heisman odds or any other player at Lucky Rebel, one of the top online bookmakers for futures betting on college football.
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