With the final Grand Slam approaching on the tennis calendar, the men’s 2025 US Open winner odds are available now. World No. 1 Jannik Sinner is searching for back-to-back US Open titles after taking down Taylor Fritz in the finals last year.
Is he the top wager, or can Carlos Alcaraz bounce back and extract some payback after losing Wimbledon to his rival? I explore the latest winner odds, analyze the favorites, and make my ATP US Open predictions.
US Open 2025 Men’s Winner Odds
Here are the men’s US Open tennis betting odds, courtesy of Bovada:
| PLAYER | ODDS |
|---|---|
| Jannik Sinner | EVEN |
| Carlos Alcaraz | +175 |
| Alexander Zverev | +1200 |
| Novak Djokovic | +1400 |
| Jack Draper | +1800 |
| Ben Shelton | +2000 |
| Daniil Medvedev | +2800 |
| Taylor Fritz | +3000 |
| Jakub Mensik | +5000 |
Jannik Sinner (EVEN) is the betting favorite to win the 2025 US Open. At +100, Sinner is a virtual coin flip to win a second consecutive title in Queens and the fourth major of his career. In short, Sinner has a 50% implied probability to oust the field.
Aside from Sinner, the bookies see Carlos Alcaraz (+175) as his only competition at the USTA Billie Jean King National Tennis Center. Sinner’s main rival has a 36.4% implied chance, so a decent drop from the Italian. At 19 years old, Alcaraz won his first US Open title in 2019, but hasn’t captured the tournament since.
The best tennis betting sites don’t have any faith in the rest of the players in this field. Alexander Zverev (+1200) has the third-shortest odds to win the US Open, while Novak Djokovic (+1400) owns just a 6.7% implied chance. Djokovic at +1400 is something you thought you’d never see!
You can find up-to-date ATP US Open men’s odds at Bovada by navigating to All Sports > Tennis > Futures > US Open.
2025 US Open Men’s Favorites
Out of a field of 128 singles players, only two men stand out as betting favorites to win the ATP US Open in Queens, NY. The other 126 are all underdogs and have long-shot odds!
Let’s break down the top favorites before diving into my best 2025 US Open men’s picks:
Jannik Sinner (EVEN)
The 24-year-old Italian has a bright future ahead of him, but he’s already accomplished so much in his young career. Sinner has already won two Australian Opens, one Wimbledon title, and took home the US Open last year.
With Djokovic in the final stages of his career, the Sinner and Alcaraz rivalry is here and going to be with us for the next decade. Before another young talent develops, it’s going to be Sinner and Alcaraz mentioned as favorites for the foreseeable future.
As it stands, Sinner is the king of the hard surface, though. He is a strong shout above the rest of the ATP Tour on a hard court. Sinner has developed dramatically over the last two years, with a record of 63-4 in 67 matches! That’s an incredible mark to showcase Sinner’s dominance on hard courts.
JANNIK SINNER IS A WIMBLEDON CHAMPION 🏆#Wimbledon pic.twitter.com/7wpC5lOj9o
— Roland-Garros (@rolandgarros) July 13, 2025
Additionally, in 2025, Sinner has lost just three sets out of 34 hard-court matches. It isn’t just on this surface, though, as Sinner has been mowing down opponents regardless of where it’s being played, including the grass at Wimbledon. Overall, he’s No. 1 on the ATP Tour, with a record of 92-11 and 11,480 points.
He dropped out of the final at the Cincinnati Open due to an illness, but was favored to beat Alcaraz. The Italian reportedly went into the match with a high fever and didn’t recover in time and ultimately bowed out in the first set. Don’t expect this to impact his ability to play in the US Open.
Carlos Alcaraz (+175)
Alcaraz will vie for his second major title this year after winning the French Open in June. At only 22 years old, Alcaraz already has five Grand Slams on his resume.
Still, hard courts haven’t been kind to him in recent years. Since winning the US Open in 2022, the Spaniard hasn’t kept pace on hard courts. It’s important to note that he’s still dominating most of his opponents. However, against elite players like Sinner, he tends to falter and fold.
He owns a 45-12 record over the last two years on a hard court, which looks outstanding. Despite winning the HSBC Championship and Cincinnati Open, he did it against a weak field, and then Sinner withdrew to hand him the victory.
Carlos Alcaraz signed the camera after Jannik Sinner retired in the Cincinnati final:
"Sorry Jannik " pic.twitter.com/OAqyKKY0UT
— The Sports Geek (@TheSports_Geek) August 18, 2025
Alcaraz is tremendous on his feet, and it’s slightly tougher to move around on the clay and grass courts. This is where he has a built-in advantage. When you put him on a hard court, that edge disappears because Sinner is solid on his feet there as well.
All of that said, Alcaraz is likely the only player in this tournament who has the tools to beat Sinner. With +175 odds to win the men’s US Open, that’s about where the No. 2 in the world should be in this event!
Best US Open 2025 Sleepers
Sinner and Alcaraz are on a collision course for one another at this year’s US Open. However, it’s always wise to consider some of the long shots for your US Open men’s betting picks.
Before locking in your best bet, here are two underdogs worth considering:
2025 US Open Men’s Predictions and Betting Pick
With Alcaraz and Sinner so ahead of this field, the winner is most likely one of these two players. In the end, though, Sinner should have the upper hand on a court where he made it look awfully easy last year.
The Italian’s game has improved considerably on his favorite surface, and I suspect he won’t be touched in Queens. Sinner’s dominance on hard courts has been well-documented, and it’s incredible when you look at his record of 63-4 over the last two years!
Alcaraz won’t be that far behind, but Sinner is going to have the extra kick when it matters most. Now, even odds may not appear like the best value, but consider the fact that Sinner will be roughly a -200 favorite if they meet in the finals.
He closed at -205 in the Cincinnati Open match but withdrew due to illness. Expect Sinner to be over that flu bug and be in top form for this tournament, though. In short, Sinner is a strong play as the best 2025 US Open men’s prediction to win!
Who Is Your Men’s US Open 2025 Pick?
Which player is your top US Open men’s tennis winner prediction? Do you have Alcaraz, Sinner, or an upset contender winning at Flushing Meadows? No matter who you expect to win, the odds on him will be available at Bovada!
The sportsbook offers winner odds for both the men’s and women’s events, and you can expect plenty of markets for all US Open tennis matches.
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