The opening NFL Week 15 odds are now available for wagering at NFL betting sites. We’ve evaluated every game on the board and made our Week 15 NFL predictions.
As the season winds down, there isn’t much margin for error in the NFL. Teams on the playoff bubble can’t afford many more lapses down the stretch in December.
Let’s dive into the latest NFL odds and lock in our best football bets for this critical week. All NFL Week 15 odds are courtesy of Bovada:
Los Angeles Chargers vs. Las Vegas Raiders Odds
| TEAM | SPREAD | MONEYLINE | TOTAL |
|---|---|---|---|
| Los Angeles Chargers | +3 (-115) | +135 | Over 33.5 (-110) |
| Las Vegas Raiders | -3 (-105) | -160 | Under 33.5 (-110) |
As head coach Brandon Staley and the Chargers walk a thin line, they face a must-win scenario over the Raiders at Allegiant Stadium. It might be without Justin Herbert after he suffered a fractured finger
If Herbert can’t start, Easton Stick will be under center after taking over for Herbert against the Broncos. Despite this possibility, laying a field goal on the Raiders given their offensive woes isn’t a strong value bet.
Consider backing the Chargers as road underdogs in Las Vegas on Thursday Night Football.
Chargers vs. Raiders Predictions:
- Point Spread Bet: Los Angeles Chargers +3 (-115)
- Moneyline Bet: Los Angeles Chargers (+135)
- Over-Under Bet: Under 33.5 (-110)
Minnesota Vikings vs. Cincinnati Bengals Odds
| TEAM | SPREAD | MONEYLINE | TOTAL |
|---|---|---|---|
| Minnesota Vikings | +3 (-105) | +170 | Over 39.5 (-110) |
| Cincinnati Bengals | -3 (-115) | -200 | Under 39.5 (-110) |
The Vikings and Bengals are one of the most evenly balanced matchups of the week on paper. NFL Week 15 odds at football betting sites back up this assertion as well.
As a slight underdog, the value has to be on the Bengals at +1. Bengals’ QB Jake Browning is coming along nicely and developing a solid rapport with Ja’Marr Chase.
With a healthy Chase giving Browning a top target, this offense is still dangerous despite Joe Burrow’s injury. Look for the Bengals to edge out the Vikings at home in the first of three Saturday games.
Vikings vs. Bengals Predictions:
- Point Spread Bet: Cincinnati Bengals -3 (-115)
- Moneyline Bet: Cincinnati Bengals (-200)
- Over-Under Bet: Over 39.5 (-110)
Pittsburgh Steelers vs. Indianapolis Colts Odds
| TEAM | SPREAD | MONEYLINE | TOTAL |
|---|---|---|---|
| Pittsburgh Steelers | +2.5 (-110) | +130 | Over 42.5 (-110) |
| Indianapolis Colts | -2.5 (-110) | -150 | Under 42.5 (-110) |
The Colts are underdogs to win the AFC South, but it’s not over yet. Depending on Trevor Lawrence’s ankle injury, the Texans and Colts might have a chance to steal the division title.
This is a great spot for the Colts to pick up a big win. The Colts’ secondary has experienced some tough moments this season. However, the Steelers are at a disadvantage with Mitch Trubisky and Mason Rudolph as their only options at QB.
The Colts’ defense should look fairly sharp in Week 15. In one of the Colts’ most important games of the year, expect Gardner Minshew to step up to deliver a win.
Steelers vs. Colts Predictions:
- Point Spread Bet: Indianapolis Colts -2.5 (-110)
- Moneyline Bet: Indianapolis Colts (-150)
- Over-Under Bet: Under 42.5 (-110)
Denver Broncos vs. Detroit Lions Odds
| TEAM | SPREAD | MONEYLINE | TOTAL |
|---|---|---|---|
| Denver Broncos | +3.5 (-110) | +170 | Over 46.5 (-110) |
| Detroit Lions | -3.5 (-110) | -200 | Under 46.5 (-110) |
The Broncos and Lions will wrap up the Saturday card with a showdown at Ford Field. The visiting Broncos are in search of a playoff berth, while the Lions are in contention for home-field in the playoffs and the NFC North title.
On a Saturday night in Detroit, look for this to be a tough environment for Russell Wilson to operate in at Ford Field. Jared Goff and his multitude of offensive weapons should have a productive evening.
Too much Lions’ firepower will likely leave the Broncos behind by 8 or 10 points. Expect a bounce-back performance after struggling at Soldier Field last week.
Broncos vs. Lions Predictions:
- Point Spread Bet: Detroit Lions -3.5 (-110)
- Moneyline Bet: Detroit Lions (-200)
- Over-Under Bet: Over 46.5 (-110)
Atlanta Falcons vs. Carolina Panthers Odds
| TEAM | SPREAD | MONEYLINE | TOTAL |
|---|---|---|---|
| Atlanta Falcons | -3 (-110) | -160 | Over 34.5 (-110) |
| Carolina Panthers | +3 (-110) | +135 | Under 34.5 (-110) |
The Falcons could be going to the playoffs as a .500 team or even worse. As the NFC South limps to the finish line, it’s not going to take much to win this division.
The Panthers’ best team strength is in their secondary. Atlanta will pound the ball, but Desmond Ridder has to come up with a play at some point.
We foresee the Panthers making the Falcons even more one-dimensional than they already are at Bank of America Stadium. In what should be an ugly football game, the Panthers have a good shot at a small upset.
Falcons vs. Panthers Predictions:
- Point Spread Bet: Carolina Panthers +3 (-110)
- Moneyline Bet: Carolina Panthers (+135)
- Over-Under Bet: Over 34.5 (-110)
Chicago Bears vs. Cleveland Browns Odds
| TEAM | SPREAD | MONEYLINE | TOTAL |
|---|---|---|---|
| Chicago Bears | +2.5 (-110) | +115 | Over 36.5 (-110) |
| Cleveland Browns | -2.5 (-110) | -135 | Under 36.5 (-110) |
The Browns and Bears came exploding out of the blocks in Week 14. However, before the end of the first half, the Jaguars and Lions were back in the contest.
This week, the Browns’ defense should take command of the matchup. Justin Fields was banged up pretty good in a divisional game versus the Lions.
The league-leading Browns’ defense won’t make it any easier on the Bears. We are on the Browns as a small home favorite.
Bears vs. Browns Predictions:
- Point Spread Bet: Cleveland Browns -2.5 (-110)
- Moneyline Bet: Cleveland Browns (-135)
- Over-Under Bet: Under 36.5 (-110)
Houston Texans vs. Tennessee Titans Odds
| TEAM | SPREAD | MONEYLINE | TOTAL |
|---|---|---|---|
| Houston Texans | +1.5 (-110) | +100 | Over 37.5 (-110) |
| Tennessee Titans | -1.5 (-110) | -120 | Under 37.5 (-110) |
Following a tough matchup against the Jets’ swarming defense, the Texans could be without their starting QB in Nashville, Tennessee. With C.J. Stroud in concussion protocol, Davis Mills could be up next.
The Titans have been a different team at home this season. They are 4-1 against the spread (ATS) and 3-1 ATS as a home underdog. Watch the injury report throughout the week, but currently, the Titans are the pick.
Texans vs. Titans Predictions:
- Point Spread Bet: Tennessee Titans -1.5 (-110)
- Moneyline Bet: Tennessee Titans (-120)
- Over-Under Bet: Under 37.5 (-110)
New York Giants vs. New Orleans Saints Odds
| TEAM | SPREAD | MONEYLINE | TOTAL |
|---|---|---|---|
| New York Giants | +6 (-110) | +215 | Over 36.5 (-110) |
| New Orleans Saints | -6 (-110) | -260 | Under 36.5 (-110) |
The Giants head to the Caesars Superdome on a short week after hosting the Green Bay Packers on Monday Night Football. Giants’ QB Tommy DeVito has earned the right to remain with the first-team offense, but he will make some mistakes on the road.
New Orleans is coming off a confidence-boosting 28-6 win over the Panthers. Carolina is having a rough go of it this season, but it was an impressive effort by the Saints to remain in contention.
The Saints’ Week 15 NFL odds are too short at sports betting sites. We don’t see the Giants being fully prepared for this one.
Giants vs. Saints Predictions:
- Point Spread Bet: New Orleans Saints -6 (-110)
- Moneyline Bet: New Orleans Saints (-260)
- Over-Under Bet: Under 36.5 (-110)
New York Jets vs. Miami Dolphins Odds
| TEAM | SPREAD | MONEYLINE | TOTAL |
|---|---|---|---|
| New York Jets | +12 (-110) | +550 | Over 40.5 (-110) |
| Miami Dolphins | -12 (-110) | -800 | Under 40.5 (-110) |
The Jets are coming off an impressive display at home against the Texans for a 30-6 win. Zach Wilson returned to the starting lineup after getting benched last month.
However, the good feelings should come to a halt at Hard Rock Stadium in Florida. The Jets fall victim to the high-octane Dolphins in a letdown spot.
Jets vs. Dolphins Predictions:
- Point Spread Bet: Miami Dolphins -12 (-110)
- Moneyline Bet: Miami Dolphins (-800)
- Over-Under Bet: Under 40.5 (-110)
Tampa Bay Buccaneers vs. Green Bay Packers Odds
| TEAM | SPREAD | MONEYLINE | TOTAL |
|---|---|---|---|
| Tampa Bay Buccaneers | +3.5 (-110) | +130 | Over 42.5 (-110) |
| Green Bay Packers | -3.5 (-110) | -150 | Under 42.5 (-110) |
The Buccaneers overcame a late deficit in Atlanta to pull even with the 6-7 Saints and Falcons in the NFC South. That is good for a three-way tie going into Week 15.
In a tough place to win at Lambeau Field, this game should prove to be more difficult against an emerging Packers’ squad. It took Packers’ QB Jordan Love a few months to get comfortable in the offense, but they are off and running now.
We foresee Baker Mayfield having a rough start against an underrated Packers’ defense. Rashan Gary should have a productive afternoon.
Buccaneers vs. Packers Predictions:
- Point Spread Bet: Green Bay Packers -3.5 (-110)
- Moneyline Bet: Green Bay Packers (-150)
- Over-Under Bet: Over 42.5 (-110)
Kansas City Chiefs vs. New England Patriots Odds
| TEAM | SPREAD | MONEYLINE | TOTAL |
|---|---|---|---|
| Kansas City Chiefs | -10 (-110) | -480 | Over 37.5 (-110) |
| New England Patriots | +10 (-110) | +325 | Under 37.5 (-110) |
The Chiefs are coming off a hard-fought battle against the Bills at Arrowhead. As we’ve noted in the past, the Chiefs have reinvented themselves as a defensive team.
Patrick Mahomes throwing for 300+ yards and three touchdowns on a weekly basis hasn’t happened this season. With some extra time to prepare following a 21-18 win on Thursday Night Football, the Patriots’ defense should be in good form.
As bad as the Patriots have been offensively, laying double digits on the Chiefs against their defense isn’t the best value. Tyreek Hill and even JuJu Smith-Schuster’s absence is catching up to the Chiefs.
Chiefs vs. Patriots Predictions:
- Point Spread Bet: New England Patriots +10 (-110)
- Moneyline Bet: Kansas City Chiefs (-550)
- Over-Under Bet: Under 37.5 (-110)
San Francisco 49ers vs. Arizona Cardinals Odds
| TEAM | SPREAD | MONEYLINE | TOTAL |
|---|---|---|---|
| San Francisco 49ers | -13.5 (-110) | -850 | Over 46 (-110) |
| Arizona Cardinals | +13.5 (-115) | +590 | Under 46 (-110) |
The 49ers weren’t at their best against the Seahawks, but pulled away for a 28-16 win at Levi’s Stadium. Seahawks’ QB Drew Lock filled in well enough after having to replace Geno Smith due to a groin injury.
The Cardinals are coming off a bye week, after upsetting the Steelers two weeks ago by a score of 24-10. As the 49ers look ahead to the Ravens next week, the Cardinals should be the more interested team in this matchup.
Expect the 49ers to go through the motions to win, but fail to cover the point spread.
49ers vs. Cardinals Predictions:
- Point Spread Bet: Arizona Cardinals +13.5 (-110)
- Moneyline Bet: San Francisco 49ers (-850)
- Over-Under Bet: Under 46 (-110)
Washington Commanders vs. Los Angeles Rams Odds
| TEAM | SPREAD | MONEYLINE | TOTAL |
|---|---|---|---|
| Washington Commanders | +6.5 (-110) | +215 | Over 46.5 (-110) |
| Los Angeles Rams | -6.5 (-110) | -275 | Under 46.5 (-110) |
The Rams impressed on the road at Baltimore, but were unable to get the upset in a 37-31 OT loss. Matthew Stafford found a weak link in the Ravens’ secondary and is one of the few QBs that has hit the defense hard.
Despite the loss, the Rams are still confident that they can get into the playoffs. With the porous Commanders’ secondary coming to town, Stafford and the Rams should improve their odds in Week 15.
Look for Stafford to dice up the Commanders for an 8-or-10-point win by the Rams.
Commanders vs. Rams Predictions:
- Point Spread Bet: Los Angeles Rams -6.5 (-110)
- Moneyline Bet: Los Angeles Rams (-275)
- Over-Under Bet: Over 46.5 (-110)
Dallas Cowboys vs. Buffalo Bills Odds
| TEAM | SPREAD | MONEYLINE | TOTAL |
|---|---|---|---|
| Dallas Cowboys | +1 (-110) | +100 | Over 49 (-110) |
| Buffalo Bills | -1 (-110) | -120 | Under 49 (-110) |
The Bills are back home after a thrilling win over the Chiefs at Arrowhead. They have a marquee matchup on the schedule for the second consecutive week.
The same can be said for the Cowboys, who are coming off a Sunday Night Football appearance against their NFC East rivals, the Eagles.
Buffalo is not an easy place to win at in December. It should be mild on Sunday, but this should be a hostile environment for the Cowboys.
For our NFL Week 15 predictions, we like the Bills to come out on top as they look to get back into the Super Bowl 58 conversation.
Cowboys vs. Bills Predictions:
- Point Spread Bet: Buffalo Bills -1 (-110)
- Moneyline Bet: Buffalo Bills (-120)
- Over-Under Bet: Under 49 (-110)
Baltimore Ravens vs. Jacksonville Jaguars Odds
| TEAM | SPREAD | MONEYLINE | TOTAL |
|---|---|---|---|
| Baltimore Ravens | -3.5 (-110) | -135 | Over 40.5 (-110) |
| Jacksonville Jaguars | +3.5 (-110) | +115 | Under 40.5 (-110) |
Stafford showed how to beat the Ravens’ defense. Will Trevor Lawrence follow suit and do the same on Sunday Night Football?
Last week, all three contenders in the AFC South lost. The Colts, Texans, and Jaguars passed on chances for a big win in Week 14.
After a disappointing loss to the Browns, expect Jacksonville to push the Ravens to the limit in this one. In the spotlight of a primetime game, Lawrence and the Jaguars win a close one by a field goal at home.
Ravens vs. Jaguars Predictions:
- Point Spread Bet: Jacksonville Jaguars +3.5 (-110)
- Moneyline Bet: Jacksonville Jaguars (+115)
- Over-Under Bet: Under 40.5 (-110)
Philadelphia Eagles vs. Seattle Seahawks Odds
| TEAM | SPREAD | MONEYLINE | TOTAL |
|---|---|---|---|
| Philadelphia Eagles | -4.5 (-110) | -210 | Over 47 (-110) |
| Seattle Seahawks | +4.5 (-110) | +175 | Under 47 (-110) |
Monday Night Football might be a game you want to wait on until you hear about the state of the Seahawks’ QB situation. If Smith can start, the Seahawks might be able to make a game of this.
Nevertheless, as of right now, the Eagles look like the best bet. Last week, the Eagles didn’t have their best effort against the Cowboys.
Anticipate a much different Eagles’ team in this less difficult assignment at Lumen Field in Seattle, Washington.
Eagles vs. Seahawks Predictions:
- Point Spread Bet: Philadelphia Eagles -4.5 (-110)
- Moneyline Bet: Philadelphia Eagles (-210)
- Over-Under Bet: Under 47 (-110)
Best NFL Bets This Week
Let’s briefly look at our NFL best bets for Week 15. We locked in two of our early best NFL bets on Monday at Bovada:
Indianapolis Colts (-2.5)
On Saturday afternoon, the Steelers and Colts collide in a matchup with playoff implications at Lucas Oil Stadium. The Steelers and Colts both have AFC Conference Championship aspirations, but neither side looked like a contender in Week 14.
After struggling to threaten the Patriots’ defense on Thursday Night Football, Mike Tomlin might be considering a switch to Rudolph. Regardless of the QB, the Steelers’ inconsistent offense should stall out on the road against the Colts.
Despite the loss, the Colts are 4-1 ATS in their previous five games. Additionally, they are 4-0 ATS as a favorite in 2023. After a loss, they’ve gone 4-1 ATS in their next five games.
Minshew and the Colts are in a solid position to bounce back against a lifeless Steelers’ offense at home this Saturday.
New Orleans Saints (-6)
The Giants face a tough assignment after going head-to-head with the Packers on Monday Night Football. As well as DeVito has stepped in off the bench and given the Giants a spark, there will be growing pains.
We don’t trust DeVito after being in the spotlight on a short week. The Saints are far from a perfect team. However, this is a big week for them, as they remain in the NFC South race for the divisional title.
Last week, they were able to pick up some much-needed confidence with a blowout win over the Panthers. Beating up on the Panthers isn’t necessarily impressive, but it could be a springboard for the rest of the season.
Blowing out the Giants in this situation wouldn’t make for a signature win, either. This season on the road, the Giants are just 2-5 ATS. Expect the Saints to have the advantage at home.
Best NFL Week 15 Parlay
We will finish our NFL Week 15 betting preview with the best NFL Week 15 parlay picks. For Week 15, we are playing our NFL parlay tickets at Bovada.
With superior NFL parlay odds, it’s worth signing up to get their exclusive free sports betting bonus of $250 or $750 in crypto deposit bonuses.
The following NFL Week 15 parlay pays $1,565.61 on a $100 wager at Bovada:
- Indianapolis Colts -2.5 (-110)
- New Orleans Saints -6 (-110)
- Tennessee Titans -1.5 (-110)
- Los Angeles Rams (-300)
- Jacksonville Jaguars +3.5 (-120)
