MLB Divisional Series 2025 Betting Preview: ALDS and NLDS Odds, Predictions, Best Bets

New York Yankees vs. Toronto Blue Jays Preview: ALDS Odds and Analysis

• • Toronto Blue Jays (+130)
  • New York Yankees (-150)

The New York Yankees enter Game 1 as the odds-on favorites to beat the Toronto Blue Jays. As a -150 favorite, the Yankees have a 60% implied probability to win despite not having home-field advantage.

The Blue Jays won the AL East after edging out the Yankees on the final day of the regular season. They won four straight games to clinch the top spot in the last second, with no room for error.

Toronto won the regular season series against the Yanks and were therefore granted the tiebreaker with both clubs at 94-68. They were the more dominant team, as their 8-5 record suggests, and it ended up paying off on the final day of the season.

It’s a massive help to the Blue Jays, who were the best team in the American League at home. They finished 54-27 as opposed to the Yankees’ 44-37 record on the road. Note that the Blue Jays recorded the best batting average in baseball at .265.

At the Rogers Centre in Toronto, that number jumps to .271 with a .340 OBP. Additionally, the Blue Jays hit 104 home runs at home, with 87 long balls on the road. While Toronto doesn’t have Aaron Judge, they do have George Springer, who has been incredibly clutch.

George Springer’s massive bounce-back season has helped catapult the @BlueJays to the top of the American League:

.302 AVG
.391 OBP
29 HR
78 RBI
16 SB

(MLB x Essilor) pic.twitter.com/AfO8gdWNcA

— MLB (@MLB) September 19, 2025

Springer had an outstanding regular season with a .309 batting average, 32 home runs, and 84 RBIs. Whenever the Jays have needed a big hit, he has delivered. Expect Springer to be a catalyst in a big spot for the Blue Jays.

Detroit Tigers vs. Seattle Mariners Preview: ALDS Odds and Analysis

• • Detroit Tigers (+153)
  • Seattle Mariners (-175)

After blowing a 15.5-game lead and the AL Central, the Tigers managed to clinch a playoff berth at the wire and then win on the road in the AL Wild Card against the Cleveland Guardians. However, the latest MLB Divisional Series odds don’t have them going any further.

The Seattle Mariners are the largest favorites to advance to the next round. At -175, the Mariners have a 63.6% implied probability to beat the Detroit Tigers in the ALDS. The Mariners have snuck up on some people and are who I regard as the most underrated in the postseason.

Dan Wilson’s club went 90-72 and held a three-game advantage over the Houston Astros. They finished 51-30, with the second-best home record in the American League. T-Mobile Park isn’t an easy place to win at, and the Mariners have the weapons to defend their home ground.

The Mariners have a deep starting rotation that is more consistent than the Tigers. While the Tigers can rely on Tarik Skubal every outing, you can’t say the same for the rest. Jack Flaherty was fantastic in Game 3 of the Wild Card, but you can’t rely on him and Casey Mize to consistently deliver.

However, the Mariners’ Luis Castillo (3.54 ERA), George Kirby (4.21 ERA), and Logan Gilbert (3.44 ERA) are an outstanding trio. Kirby had a couple of rocky starters but has otherwise been in top form recently.

CAL RALEIGH'S 60TH HOMER OF THE SEASON GOT OUT IN A HURRY 😱 pic.twitter.com/P47l5L4Pjp

— SportsCenter (@SportsCenter) September 25, 2025

With Cal Raleigh leading the league in homers with 60, the Mariners were third in MLB in home runs this season. The Mariners’ 238 long balls easily cleared the Tigers’ 198 deep bombs. Raleigh could be the difference in this series, as the Tigers don’t have a true difference-maker in the batter’s box like him.

Chicago Cubs vs. Milwaukee Brewers Preview: NLDS Odds and Analysis

• • Chicago Cubs (+105)
  • Milwaukee Brewers (-125)

The odds for the NLDS between the Cubs and Brewers indicate we are likely to have a competitive series. The Brewers have a 55.6% implied probability to win and go to the NLCS.

They caught fire after the All-Star break and ripped off two winning streaks of at least 10 games in July and then again in August. In mid-August, the Brewers set a franchise record 14-game win streak.

Did the Brewers peak much too early, though? In September, the Brewers went just 12-12, and they lost plenty of their momentum. They were barely mentioned in the final month of the regular season. Additionally, the Cubs were one of the rare clubs that had a winning record against the Brewers at 7-6.

They concluded the season with a record of 4-6 in their final 10 games but managed to hold on for the best record in the National League at 97-65. The Cubs weren’t the hottest to finish the season, either, but they are coming off a huge Game 3 victory over the San Diego Padres.

Momentum and confidence will be sky-high for the Cubs in the NLDS. The Brewers have superior pitching on paper, but the Cubs are more well-balanced offensively and on the mound. The Cubs have a top 10 offense, third with 771 RBIs, while the pitching is ninth with a 3.79 ERA.

MICHAEL BUSCH.

GOODBYE! #POSTSEASON pic.twitter.com/qMIRao3NQW

— MLB (@MLB) October 2, 2025

Milwaukee is just 22nd with 166 home runs in the regular season. Conversely, the Cubs are sixth in home runs with 223. The Cubs have six hitters with a minimum of 22 home runs. Three went deep in the Wild Card against the Padres, including Michael Busch, Carson Kelly, and Seiya Suzuki.

Los Angeles Dodgers vs. Philadelphia Phillies Preview: NLDS Odds and Analysis

• • Philadelphia Phillies (+102)
  • LA Dodgers (-122)

In a series that is most likely to get the highest viewership, the Dodgers and Phillies square off in a heavyweight matchup in the NLDS. The Dodgers are favored with odds of -122 and a 55% implied chance. Note that this is the lowest probability of any team in the divisional round.

The Dodgers didn’t have a picture-perfect regular season campaign. In fact, it was well below expectations of what most pundits projected. The defending World Series champs wrapped up the regular season with a 93-69 mark. For most teams, that would be fantastic, but the Dodgers never looked unstoppable.

That was in large part due to injuries, with multiple players in and out of the lineup and the pitching staff. Chemistry was a major problem throughout the year, but they have found their stride now. After going 8-2 in their final 10 regular-season matchups, the Dodgers swept the Reds in blowouts of 8-4 and 10-5.

The team is much healthier than it was earlier in the season, and they are playing with purpose and confidence now. Despite being the only team to avoid a third game, the Dodgers led the Wild Card with five home runs and 17 RBIs! The Dodgers are back.

Shohei Ohtani's 454-foot blast is the longest @Dodgers #Postseason homer in the Statcast Era (since 2015)! pic.twitter.com/WnPjFyHlxv

— MLB (@MLB) October 1, 2025

Additionally, despite the regular season woes, the Dodgers were first in the National League in home runs and RBIs. While the Phillies have Kyle Schwarber and Bryce Harper, they finished fourth in the National League in RBIs and fifth in home runs. Aside from Schwarber, the power bats were fairly inconsistent.