The 2023 NFL Week 5 odds are on the board at your favorite NFL betting sites. We are analyzing the opening odds and revealing our best NFL Week 5 predictions.
The Sports Geek has NFL Week 5 picks for every matchup. Not only are we including our best NFL Week 5 point spreads bets, but we also have moneyline and Over-Under wagers as well.
Additionally, we will finish with our best NFL Week 5 bet and a parlay for those NFL bettors that like some extra hot sauce on their weekly action. If you are considering betting on every game, ensure that you are exercising proper bankroll management before locking in your wagers.
The following NFL Week 5 odds are courtesy of Bovada.
Chicago Bears vs. Washington Commanders Odds
| TEAM | SPREAD | MONEYLINE | TOTAL |
|---|---|---|---|
| Chicago Bears | +6 (-115) | +220 | Over 45 (-115) |
| Washington Commanders | -6 (-105) | -270 | Under 45 (-105) |
The Washington Commanders have had a difficult schedule over the last two weeks. In Week 3, the Commanders welcomed the Buffalo Bills to FedExField.
Following the blowout loss, the Commanders were at Philadelphia for a Week 4 showdown with the Eagles. That was a tough stretch for first-year starting QB Sam Howell.
However, Thursday Night Football should be a solid spot for Howell to regain his footing.
Expect big games from Terry McLaurin and Curtis Samuel against the Bears’ secondary. Meanwhile, the Commanders’ pass rush should pressure Justin Fields into mistakes on their home field.
Bears vs. Commanders Prediction:
- Point Spread Bet: Washington Commanders -6 (-105)
- Moneyline Bet: Washington Commanders (-270)
- Over-Under Bet: Over 45 (-115)
Jacksonville Jaguars vs. Buffalo Bills Odds
| TEAM | SPREAD | MONEYLINE | TOTAL |
|---|---|---|---|
| Jacksonville Jaguars | +5 (-110) | +180 | Over 48 (-110) |
| Buffalo Bills | -5 (-110) | -220 | Under 48 (-110) |
The Buffalo Bills fly overseas to meet with the Jacksonville Jaguars at the home of the Tottenham Spurs. For the second consecutive week, the Jaguars have a game in London in an NFL International Series matchup.
The travel schedule will be a little more hectic for the Bills after a marquee showing against the Miami Dolphins. After blowing out the Dolphins in a signature win, they have to fly overseas to the UK.
Expect the Bills to survive with a late win, but the Jaguars are in a position to be competitive in Week 5.
Jaguars vs. Bills Prediction:
- Point Spread Bet: Jacksonville Jaguars +5 (-110)
- Moneyline Bet: Buffalo Bills (-220)
- Over-Under Bet: Under 48 (-110)
Baltimore Ravens vs. Pittsburgh Steelers Odds
| TEAM | SPREAD | MONEYLINE | TOTAL |
|---|---|---|---|
| Baltimore Ravens | -3.5 (-105) | -180 | Over 40 (-110) |
| Pittsburgh Steelers | +3.5 (-115) | +155 | Under 40 (-110) |
In one of the AFC’s greatest rivalries over the last two decades, the Baltimore Ravens and Pittsburgh Steelers clash at Acrisure Stadium in Pittsburgh.
The last six matchups between the Ravens and Steelers have been decided by less than a touchdown. In their previous four meetings, the games were decided by a field goal or less.
The Steelers have won five of their last six games against the Ravens. Siding with the home underdog is always a wise bet in this rivalry series.
T.J. Watt is the 1st player to record 6 sacks and have a defensive TD in a team’s first 3 games of a season since individual sacks were first tracked in 1982. pic.twitter.com/7fJ4mPJ457
— ESPN Stats & Info (@ESPNStatsInfo) September 25, 2023
Ravens vs. Steelers Prediction:
- Point Spread Bet: Pittsburgh Steelers +3.5 (-115)
- Moneyline Bet: Pittsburgh Steelers (+155)
- Over-Under Bet: Under 40 (-110)
Carolina Panthers vs. Detroit Lions Odds
| TEAM | SPREAD | MONEYLINE | TOTAL |
|---|---|---|---|
| Carolina Panthers | +7.5 (-105) | +300 | Over 43.5 (-110) |
| Detroit Lions | -7.5 (-115) | -400 | Under 43.5 (-110) |
The Lions return home to Ford Field following a successful NFC North rivalry matchup at Lambeau Field on Thursday Night Football.
It was an impressive display by the Lions, as they bullied the Packers in the trenches on both sides of the ball. This week, the Lions have their eyes set on rookie QB Bryce Young.
Bovada’s NFL Week 5 odds indicate that the Lions are a touchdown favorite over the Panthers. Young has to get rid of the ball quickly against the Lions’ strong pass rush, or it could get ugly early.
In our opinion, the Lions should pull out the win with their rushing game and defensive line. The Panthers have had trouble defending the run, and it’s not going to get better versus David Montgomery and Jahmyr Gibbs.
And, oh yeah, Jameson Williams could be back early to give an offense already clicking more firepower.
David Montgomery rushed for 121 yards and a career-high 3 touchdowns on 32 carries in the Lions 34-20 won over the Packers.
Montgomery’s 113 yards after contact is the most he’s ever gained in a single game in his career.#GBvsDET | #OnePride pic.twitter.com/EuZlj0NAWu
— Next Gen Stats (@NextGenStats) September 29, 2023
Panthers vs. Lions Prediction:
- Point Spread Bet: Detroit Lions -7.5 (-110)
- Moneyline Bet: Detroit Lions (-400)
- Over-Under Bet: Over 43.5 (-110)
Houston Texans vs. Atlanta Falcons Odds
| TEAM | SPREAD | MONEYLINE | TOTAL |
|---|---|---|---|
| Houston Texans | +2 (-110) | +110 | Over 41 (-110) |
| Atlanta Falcons | -2 (-110) | -185 | Under 41 (-110) |
The Falcons fly back home after playing the Jaguars at Wembley Stadium. The travel schedule likely isn’t going to be easy on this young Falcons squad.
They need an experienced leader to quickly get this team focused after an overseas trip, but we are not sure that it is present in Atlanta.
The Falcons depend on being physical at the point of attack on the line of scrimmage. Running the ball with Bijan Robinson and Tyler Allgeier is their game plan, which isn’t a secret to any defensive coordinator in the NFL.
After a physical battle against the Jaguars overseas, expect the Falcons to be a step slower in Week 5. C.J. Stroud and the Texans have a chance to steal another win on the road this season.
Texans vs. Falcons Prediction:
- Point Spread Bet: Houston Texans +2 (-110)
- Moneyline Bet: Houston Texans (+110)
- Over-Under Bet: Over 41 (-110)
Kansas City Chiefs vs. Minnesota Vikings Odds
| TEAM | SPREAD | MONEYLINE | TOTAL |
|---|---|---|---|
| KC Chiefs | -6 (-110) | -270 | Over 52.5 (-110) |
| Minnesota Vikings | +6 (-110) | +225 | Under 52.5 (-110) |
Expect plenty of fireworks at U.S. Bank Stadium between the Chiefs and Vikings. There should be points on the board in a high-scoring contest. We are betting on Taylor Swift not being in attendance to see it all unfold in Minnesota.
Nevertheless, Travis Kelce should have a strong performance against a beatable Vikings’ secondary. In addition to Kelce, the rest of the Chiefs offense should find room to get open in this one against the blitz.
The offense was stagnant through the first two weeks, but exploded against the Chicago Bears for 41 points. In Week 4, the Jets’ defense was able to hold them back on Sunday Night Football.
However, the Vikings do not have the Jets’ defense. Kirk Cousins won’t be able to keep pace, as the Chiefs pull away and cover over the Vikings.
Chiefs vs. Vikings Prediction:
- Point Spread Bet: KC Chiefs -6 (-110)
- Moneyline Bet: KC Chiefs (-270)
- Over-Under Bet: Over 52.5 (-110)
New Orleans Saints vs. New England Patriots Odds
| TEAM | SPREAD | MONEYLINE | TOTAL |
|---|---|---|---|
| New Orleans Saints | +1.5 (-110) | +105 | Over 40.5 (-110) |
| New England Patriots | -1.5 (-110) | -125 | Under 40.5 (-110) |
The Saints and Patriots are likely to engage in a low-scoring defensive battle at Gillette Stadium. Which defense will prevail in this physical contest?
Derek Carr is just 1-3 in four games against the Patriots in his career. Bill Belichick has had success limiting Carr in the past.
Back home following a tough time at AT&T Stadium versus the Cowboys, the Patriots’ pass rush should be the difference.
The Patriots have decent betting value as less than a field-goal favorite at home.
Saints vs. Patriots Prediction:
- Point Spread Bet: New England Patriots -1.5 (-110)
- Moneyline Bet: New England Patriots (-125)
- Over-Under Bet: Under 40.5 (-110)
Tennessee Titans vs. Indianapolis Colts Odds
| TEAM | SPREAD | MONEYLINE | TOTAL |
|---|---|---|---|
| Tennessee Titans | +1 (-110) | +100 | Over 42.5 (-110) |
| Indianapolis Colts | -1 (-110) | -120 | Under 42.5 (-110) |
You have to pick your spots with the Titans and Colts this season. There will be great situations where both of these teams are great bets, but other weeks you want to fade or stay away from both squads.
The Titans want to hand the ball off to Derrick Henry and play smash-mouth football. Ryan Tannehill does not have the arm to pass for 400 yards every week.
As we discovered versus the Ravens, the Colts can beat a run-focused offense. They couldn’t complete an impressive comeback, though rookie Anthony Richardson and the Colts showed a lot of grit.
Expect a late play from Richardson to save the Colts. It’ll be close, but the home team should win by a field goal.
Titans vs. Colts Prediction:
- Point Spread Bet: Indianapolis Colts -1 (-110)
- Moneyline Bet: Indianapolis Colts (-120)
- Over-Under Bet: Over 42.5 (-110)
New York Giants vs. Miami Dolphins Odds
| TEAM | SPREAD | MONEYLINE | TOTAL |
|---|---|---|---|
| NY Giants | +10 (-110) | +360 | Over 49.5 (-110) |
| Miami Dolphins | -10 (-110) | -500 | Under 49.5 (-110) |
In Week 4, the Dolphins were at Buffalo in the matchup of the week. The Dolphins couldn’t keep up with the Bills, but Tua Tagovailoa and company have looked unstoppable for most of this season.
The Dolphins’ Super Bowl 58 odds have reacted favorably to their hot start at football betting sites. However, this matchup against the Giants could signal a backdoor cover.
Will the Dolphins be as interested in the Giants as they were last week? Probably not. The Dolphins win, though the Giants sneak up to cover in the fourth quarter.
Giants vs. Dolphins Prediction:
- Point Spread Bet: NY Giants +10 (-110)
- Moneyline Bet: Miami Dolphins (-500)
- Over-Under Bet: Over 49.5 (-110)
Cincinnati Bengals vs. Arizona Cardinals Odds
| TEAM | SPREAD | MONEYLINE | TOTAL |
|---|---|---|---|
| Cincinnati Bengals | -5 (-110) | -200 | Over 42.5 (-110) |
| Arizona Cardinals | +5 (-110) | +170 | Under 42.5 (-110) |
The Arizona Cardinals have played well above expectations. Despite a loss to the 49ers in Week 4, the Cardinals were coming off a huge upset over the Cowboys a week earlier.
Additionally, the Cardinals were competitive in losses to the Commanders and Giants. They were expected to tank and compete for the first overall pick in the 2024 NFL Draft.
However, QB Joshua Dobbs wasn’t supposed to be this good. The former Steelers’ backup has used this opportunity to rejuvenate his career.
Laying points on the Bengals in their current mediocre state doesn’t look like a good value bet. They should edge out the Cardinals for a win on the road, but Dobbs will make this a competitive affair.
Run Dobbs Run 🏃♂️@josh_dobbs1 x #BirdGang pic.twitter.com/GeDsDcACGy
— Arizona Cardinals (@AZCardinals) September 24, 2023
Bengals vs. Cardinals Prediction:
- Point Spread Bet: Arizona Cardinals +5 (-110)
- Moneyline Bet: Cincinnati Bengals (-200)
- Over-Under Bet: Over 42.5 (-110)
Philadelphia Eagles vs. Los Angeles Rams Odds
| TEAM | SPREAD | MONEYLINE | TOTAL |
|---|---|---|---|
| Philadelphia Eagles | -5 (-110) | -220 | Over 47 (-110) |
| LA Rams | +5 (-110) | +180 | Under 47 (-110) |
Do the Rams have the offensive weapons to exploit a talented Eagles’ defense? To upset the Eagles, there typically has to be a vaunted offense on the other side.
Cooper Kupp hopes to return this week, but the Rams are still unsure about his status. The Rams will need him against the Eagles. Matthew Stafford targeting Puka Nacua 20 times won’t fool this defense.
Expect the Eagles to lean on their defensive playmakers to get the upper hand. Jalen Hurts will likely take care of the rest at SoFi Stadium.
Eagles vs. Rams Prediction:
- Point Spread Bet: Philadelphia Eagles -5 (-110)
- Moneyline Bet: Philadelphia Eagles (-220)
- Over-Under Bet: Under 47 (-110)
New York Jets vs. Denver Broncos Odds
| TEAM | SPREAD | MONEYLINE | TOTAL |
|---|---|---|---|
| NY Jets | +3 (-110) | +145 | Over 45.5 (-110) |
| Denver Broncos | -3 (-110) | -180 | Under 45.5 (-110) |
The Broncos and Bears weren’t shaping up to be an entertaining matchup. But it ended up being a surprisingly entertainings game of the week, as the Broncos completed a 21-point comeback.
Next week they have the Chiefs at Arrowhead on the schedule. This is the perfect two-game stretch for the Broncos to get on track before the Chiefs.
After going down to the wire versus the Chiefs, expect Zach Wilson to struggle in the dry air at Mile High Stadium.
Jets vs. Broncos Prediction:
- Point Spread Bet: Denver Broncos -3 (-110)
- Moneyline Bet: Denver Broncos (-170)
- Over-Under Bet: Under 45.5 (-110)
Dallas Cowboys vs. San Francisco 49ers Odds
| TEAM | SPREAD | MONEYLINE | TOTAL |
|---|---|---|---|
| Dallas Cowboys | +3 (-105) | +145 | Over 45.5 (-110) |
| San Francisco 49ers | -3 (-115) | -185 | Under 45.5 (-110) |
The showdown of the week is in the NFC at Levi’s Stadium. The absence of Cowboys’ cornerback Trevor Diggs due to a torn ACL will have a significant impact against the 49ers.
Diggs and Stephon Gilmore in the secondary would have evened this matchup. However, 49ers playmakers Deebo Samuel and Christian McCaffrey should thoroughly enjoy his absence.
Additionally, we don’t have a lot of confidence in Dak Prescott versus an aggressive 49ers’ defense. Last year, Prescott had a lot of issues trying to solve this defense in the NFL Divisional Round.
.@19problemz but breaking tackles isn’t one 😤#NYGvsSF on Prime Video
Also available on #NFLPlus https://t.co/qDMTitSHZs pic.twitter.com/HCWOD81gR7— NFL (@NFL) September 22, 2023
Cowboys vs. 49ers Prediction:
- Point Spread Bet: San Francisco 49ers -3 (-115)
- Moneyline Bet: San Francisco 49ers (-185)
- Over-Under Bet: Under 45.5 (-110)
Green Bay Packers vs. Las Vegas Raiders Odds
| TEAM | SPREAD | MONEYLINE | TOTAL |
|---|---|---|---|
| Green Bay Packers | -1 (-110) | -120 | Over 43.5 (-110) |
| Las Vegas Raiders | +1 (-110) | +100 | Under 43.5 (-110) |
The Green Bay Packers had some extra time to think about their 14-point loss to the Detroit Lions on Thursday Night Football.
Is this enough time for the Packers to get healthy? Left tackle David Bakhtiari has officially been placed on the IR after his recent absence.
Zach Tom was able to start with a knee injury, but he was ineffective against the Lions’ pass rush. Offensive guard Royce Newman was healthy, but ended up being a significant liability.
Nevertheless, the Raiders are dealing with issues of their own, including QB Jimmy Garoppolo. In what should feel like a home game for the Packers, they should bounce back with the extra time to prepare for Monday Night Football.
Packers vs. Raiders Prediction:
- Point Spread Bet: Green Bay Packers -1 (-110)
- Moneyline Bet: Green Bay Packers (-120)
- Over-Under Bet: Over 43.5 (-110)
NFL Best Bets For Week 5
In addition to the Washington Commanders winning outright over the visiting Chicago Bears, we also really like the Kansas City Chiefs to destroy the Minnesota Vikings and easily cover the -6 points.
The Vikings’ defensive coordinator, Brian Flores, has been bringing pressure with the blitz early and often this season. Flores is being forced to blitz because the Vikings are getting beat in coverage anyway.
The defense has to gamble in an attempt to force turnovers. Gambling against Patrick Mahomes and the Chiefs typically has dire consequences, though. The Chiefs’ offensive line has been terrific to provide Mahomes with extra time in the pocket.
Expect Mahomes to have a field day in the dome at U.S. Bank Stadium. Cousins will come up with a big play or two, but their one-dimensional approach will not enable them to keep pace.
The Chiefs looked lethargic against a talented Jets’ defense. That shouldn’t be the case in Minnesota.
For the final pick of our NFL Week 5 predictions, check out the Chiefs as less than a touchdown favorite at sports betting sites.
Best NFL Week 5 Parlay
The odds for NFL Week 5 present a solid opportunity to win big on a parlay bet at Bovada. You can mix and match point spreads, moneylines, and totals in one parlay.
We are playing the following five-team moneyline parlay for NFL Week 5:
- Washington Commanders (-270)
- Philadelphia Eagles (-220)
- San Francisco 49ers (-185)
- Detroit Lions (-400)
- Green Bay Packers (-120)
With this NFL Week 5 parlay, you can turn $100 into a $603.70 win! Register at Bovada to get a free 50% welcome bonus of up to $250 to use towards your first Week 5 NFL wagers.
Also, make sure that you go through our Week 5 NFL A.I. picks before locking in your wagers.
