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Michigan State Spartans vs Southern California Trojans Prediction

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For every pick our AI engine makes, it also assigns a score from 1-100 reflecting how “confident” we are each pick is likely to hit. The higher the score, the more confidence our AI models are that our picks are going to be winners.

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For every pick our AI engine makes, it also assigns a score from 1-100 reflecting how “confident” we are each pick is likely to hit. The higher the score, the more confidence our AI models are that our picks are going to be winners.

The Southern California Trojans will beat the Michigan State Spartans. The Southern California Trojans will cover the spread, and the total will go over.

Analyzing the offensive capabilities of both teams, the Trojans have a significant edge. They currently average 30.2 points per game, a stark contrast to Michigan State’s 17.5. Not only are the Trojans scoring more efficiently, but they are also demonstrating versatility with their offensive strategy, accumulating around 292 passing yards per game at a completion rate of 63.2%. In comparison, Michigan State manages just 213 passing yards per game with a lower completion percentage of 59.4%. The ability of the Trojans to stretch the field through the air while maintaining a solid ground game (averaging 145.3 rushing yards on 28.2 attempts) puts them in a favorable position to exploit any weaknesses defensively.

Defensively, the Trojans must remain aware of Michigan State’s efforts, but the Spartans simply lack the same firepower on offense. With Michigan State averaging only 17.5 points per game, the Trojans’ defense can focus on applying pressure without becoming overly concerned about a prolific scoring output from their opponents. Ultimately, the Trojans’ balanced offensive attack combined with the Spartans’ struggles will result in a dynamic game that likely ends with the total going over the projected score, sealing a comprehensive victory for Southern California.

User Consensus Picks

For every pick our AI engine makes, it also assigns a score from 1-100 reflecting how "confident" we are each pick is likely to hit. The higher the score, the more confidence our AI models are that our picks are going to be winners.

Here is the betting public’s consensus picks for the spread, moneyline, and total for today’s game. Log in with a free account and add your picks to the tally.

Spread Sep 20, 2025
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Moneyline Sep 20, 2025
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Total Sep 20, 2025

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