nfl

New England Patriots vs Buffalo Bills Prediction

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A.I. Game Picks

For every pick our AI engine makes, it also assigns a score from 1-100 reflecting how "confident" we are each pick is likely to hit. The higher the score, the more confidence our AI models are that our picks are going to be winners.

See the best bets that The Geek is favoring for today’s matchup.

Spread

For every pick our AI engine makes, it also assigns a score from 1-100 reflecting how “confident” we are each pick is likely to hit. The higher the score, the more confidence our AI models are that our picks are going to be winners.

Moneyline

For every pick our AI engine makes, it also assigns a score from 1-100 reflecting how “confident” we are each pick is likely to hit. The higher the score, the more confidence our AI models are that our picks are going to be winners.

Total

The Buffalo Bills will beat the New England Patriots. The Buffalo Bills will cover the spread, and the total will go under.

The Bills enter this matchup with an impressive offensive performance, averaging 33.3 points per game. Their balanced attack combines a substantial passing game, with approximately 249 yards per game at a completion rate near 70 percent, alongside a potent rushing offense contributing around 163.5 yards per game. This dual-threat capability positions them favorably against a Patriots defense that allows 25.5 points per game and struggles to contain both aspects of an offense.

On the other hand, the Patriots’ offense, while effective at racking up around 247 passing yards per game, operates at a lower efficiency given their completion percentage of 75.3 percent, which highlights a propensity for short and conservative passing plays. Their beleaguered ground game, only managing about 101.3 yards per game, further restricts their ability to keep pace in a scoring shootout. The strategic advantage for the Bills lies in their ability to exploit the Patriots’ defensive vulnerabilities while maintaining control of the game clock through their rushing prowess. Given these statistics, I anticipate not only a victory for the Bills but also a game total that will likely remain under, as both teams’ scoring potential, while different, leans toward a more controlled pace as the season has progressed.

User Consensus Picks

For every pick our AI engine makes, it also assigns a score from 1-100 reflecting how "confident" we are each pick is likely to hit. The higher the score, the more confidence our AI models are that our picks are going to be winners.

Here is the betting public’s consensus picks for the spread, moneyline, and total for today’s game. Log in with a free account and add your picks to the tally.

Spread Oct 5, 2025
buf ne
Moneyline Oct 5, 2025
buf ne
Total Oct 5, 2025

Game Lines

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Line History

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