Anytime TD Scorer Predictions This Week: Who Will Score a Touchdown in Week 12?

Jaxon Smith-Njigba (+100): Seahawks vs. Titans

In the matchup between the Seattle Seahawks and the Tennessee Titans, backing Jaxon Smith‑Njigba anytime to score a touchdown at +100 carries solid logic.

Smith‑Njigba is leading the league in receiving yards this season (1,146) but has just five receiving TDs, tied for 14th among his peers. Meanwhile, Seattle’s offense, coming off a sluggish performance last week, should lean into a more aggressive game plan in this one.

Jaxon Smith-Njigba on receptions of 20+ yards this season:

🔹 99.9 receiving grade (1st)
🔹 13 catches (1st)
🔹 482 yards (1st)
🔹 5 contested catches (1st) pic.twitter.com/7xot1jnjmI

— PFF Fantasy (@PFF_Fantasy) November 19, 2025

On the flip side, Tennessee’s defense presents a favorable scoring environment for Smith‑Njigba. The Titans have forced only five interceptions all season (tied for seventh‑fewest), meaning fewer turnovers and more sustained ­drives for Seattle.

In addition, Tennessee is allowing the third‑most passing touchdowns in the league (15 in 10 games) and surrendering 27.3 points per game, a ripe matchup for Seattle’s WR1.

Smith‑Njigba has also found the end zone in four of his last six starts, and one of the games he didn’t score in coincided with Seattle’s offensive struggles. With his role as the focal target again this week and the Titans’ softness in the secondary, it’s reasonable to expect he’ll find pay­dirt.

Quinshon Judkins (+100): Browns vs. Raiders

With rookie quarterback Shedeur Sanders making his first NFL start, the Browns are poised to lean heavily on the ground game this week against Las Vegas. That puts Quinshon Judkins squarely in position for a touchdown opportunity.

The Browns have one of the league’s worst passing offenses, averaging under 160 yards per game, and Sanders isn’t expected to change that overnight. Judkins will be the centerpiece of a run-first game plan designed to ease pressure off the rookie.

The matchup works in Judkins’ favor. While the Raiders hold backs to just 3.8 yards per carry, tied for the second-best mark in the NFL, they’ve still allowed 12 rushing scores this season. That total ranks among the six highest in the league, a sign their defense breaks down near the goal line.

With Cleveland committed to a run-heavy script and Judkins positioned for red-zone volume, the rookie back has a strong chance to punch one in.

Amon-Ra St. Brown (-125): Giants vs. Lions

After an uncharacteristically flat showing in Philadelphia, Detroit’s offense is due for a rebound, and Amon-Ra St. Brown figures to be at the center of it. The Lions were held to just nine points last week, well below their season average of over 29 per game.

"We have not lost faith as a team or as an offense. I think we have the right guys, right coaches, the right everything to flip this page."

Amon-Ra St. Brown gives his thoughts following the Lions' 16-9 loss to the Eagles pic.twitter.com/rhed8egJaY

— St. Brown Podcast (@StBrownPodcast) November 19, 2025

With a get-right spot against the Giants at home, expect Detroit to come out firing, and for St. Brown to be the top beneficiary.

The volume is already there. St. Brown leads the Lions in every major receiving category, including targets (94), catches (66), and yards (735). With tight end Sam LaPorta still on injured reserve, that workload should only increase.

He’ll be facing a New York defense that’s coughed up 19 passing touchdowns this year, tied for the seventh-most in the league, and has struggled to generate pressure. With Jared Goff likely to have a clean pocket, the connection with St. Brown should produce at least one trip to the end zone.

AJ Brown (+129): Eagles vs. Cowboys

With Philadelphia facing questions on the offensive line and Saquon Barkley struggling to replicate last season’s production, the Eagles will need to attack Dallas through the air. That makes AJ Brown the focal point.

He’s been openly frustrated about his involvement, and that sentiment translated into 11 targets last week. Though he didn’t score, the volume spike is a strong indicator of how the Eagles intend to use him moving forward.

The matchup couldn’t be more favorable. Dallas ranks near the bottom of the league in pass defense, allowing 249.9 yards per game and a staggering 23 passing touchdowns, the second-highest total in the NFL.

Despite their investment in the defensive front, the Cowboys haven’t shored up their secondary. That’s precisely the kind of soft coverage Brown can exploit.

If Philadelphia’s going to keep pace or take control in this divisional matchup, they’ll do it by feeding their top wideout. Brown has the skillset and the opportunity to cash this plus-money ticket.

You can combine all four anytime TD predictions in my parlay for the insane price of +1600! If you want to follow this one, I suggest doing it with a very small wager.

If you prefer a more realistic, feel free to remove one or more selections. For example, if you don’t include one of the two even odds picks, the return is still very respectable at +800.